β2 Integrins on Dendritic Cells Modulate Cytokine Signaling and Inflammation-Associated Gene Expression, and Are Required for Induction of Autoimmune Encephalomyelitis

Heterodimeric β2 integrin surface receptors (CD11a-d/CD18) are specifically expressed by leukocytes that contribute to pathogen uptake, cell migration, immunological synapse formation and cell signaling. In humans, the loss of CD18 expression results in leukocyte adhesion deficiency syndrome (LAD-)1...

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Detalles Bibliográficos
Autores principales: Bednarczyk, Monika, Bolduan, Vanessa, Haist, Maximilian, Stege, Henner, Hieber, Christoph, Johann, Lisa, Schelmbauer, Carsten, Blanfeld, Michaela, Karram, Khalad, Schunke, Jenny, Klaus, Tanja, Tubbe, Ingrid, Montermann, Evelyn, Röhrig, Nadine, Hartmann, Maike, Schlosser, Jana, Bopp, Tobias, Clausen, Björn E, Waisman, Ari, Bros, Matthias, Grabbe, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322999/
https://www.ncbi.nlm.nih.gov/pubmed/35883631
http://dx.doi.org/10.3390/cells11142188

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