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Advanced Waveguide Based LOC Biosensors: A Minireview
This mini review features contemporary advances in mid-infrared (MIR) thin-film waveguide technology and on-chip photonics, promoting high-performance biosensing platforms. Supported by recent developments in MIR thin-film waveguides, it is expected that label-free assimilated MIR sensing platforms...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323137/ https://www.ncbi.nlm.nih.gov/pubmed/35891123 http://dx.doi.org/10.3390/s22145443 |
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author | Kanjwal, Muzafar A. Ghaferi, Amal Al |
author_facet | Kanjwal, Muzafar A. Ghaferi, Amal Al |
author_sort | Kanjwal, Muzafar A. |
collection | PubMed |
description | This mini review features contemporary advances in mid-infrared (MIR) thin-film waveguide technology and on-chip photonics, promoting high-performance biosensing platforms. Supported by recent developments in MIR thin-film waveguides, it is expected that label-free assimilated MIR sensing platforms will soon supplement the current sensing technologies for biomedical diagnostics. The state-of-the-art shows that various types of waveguide material can be utilized for waveguide spectroscopic measurements in MIR. However, there are challenges to integrating these waveguide platforms with microfluidic/Lab-on-a-Chip (LOC) devices, due to poor light–material interactions. Graphene and its analogs have found many applications in microfluidic-based LOC devices, to address to this issue. Graphene-based materials possess a high conductivity, a large surface-to-volume ratio, a smaller and tunable bandgap, and allow easier sample loading; which is essential for acquiring precise electrochemical information. This work discusses advanced waveguide materials, their advantages, and disease diagnostics with MIR thin-film based waveguides. The incorporation of graphene into waveguides improves the light–graphene interaction, and photonic devices greatly benefit from graphene’s strong field-controlled optical response. |
format | Online Article Text |
id | pubmed-9323137 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93231372022-07-27 Advanced Waveguide Based LOC Biosensors: A Minireview Kanjwal, Muzafar A. Ghaferi, Amal Al Sensors (Basel) Review This mini review features contemporary advances in mid-infrared (MIR) thin-film waveguide technology and on-chip photonics, promoting high-performance biosensing platforms. Supported by recent developments in MIR thin-film waveguides, it is expected that label-free assimilated MIR sensing platforms will soon supplement the current sensing technologies for biomedical diagnostics. The state-of-the-art shows that various types of waveguide material can be utilized for waveguide spectroscopic measurements in MIR. However, there are challenges to integrating these waveguide platforms with microfluidic/Lab-on-a-Chip (LOC) devices, due to poor light–material interactions. Graphene and its analogs have found many applications in microfluidic-based LOC devices, to address to this issue. Graphene-based materials possess a high conductivity, a large surface-to-volume ratio, a smaller and tunable bandgap, and allow easier sample loading; which is essential for acquiring precise electrochemical information. This work discusses advanced waveguide materials, their advantages, and disease diagnostics with MIR thin-film based waveguides. The incorporation of graphene into waveguides improves the light–graphene interaction, and photonic devices greatly benefit from graphene’s strong field-controlled optical response. MDPI 2022-07-21 /pmc/articles/PMC9323137/ /pubmed/35891123 http://dx.doi.org/10.3390/s22145443 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kanjwal, Muzafar A. Ghaferi, Amal Al Advanced Waveguide Based LOC Biosensors: A Minireview |
title | Advanced Waveguide Based LOC Biosensors: A Minireview |
title_full | Advanced Waveguide Based LOC Biosensors: A Minireview |
title_fullStr | Advanced Waveguide Based LOC Biosensors: A Minireview |
title_full_unstemmed | Advanced Waveguide Based LOC Biosensors: A Minireview |
title_short | Advanced Waveguide Based LOC Biosensors: A Minireview |
title_sort | advanced waveguide based loc biosensors: a minireview |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323137/ https://www.ncbi.nlm.nih.gov/pubmed/35891123 http://dx.doi.org/10.3390/s22145443 |
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