Cargando…

MiRNA-Mediated Fibrosis in the Out-of-Target Heart following Partial-Body Irradiation

SIMPLE SUMMARY: Radiation exposure has been linked to non-cancer effects such as heart disease. This study aimed to investigate radiation-induced heart disease in mice where the radiation exposure was either administered to the whole body or only to the bottom third of the body (partial body). Radia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanno, Barbara, Novelli, Flavia, Leonardi, Simona, Merla, Caterina, Babini, Gabriele, Giardullo, Paola, Kadhim, Munira, Traynor, Damien, Medipally, Dinesh K. R., Meade, Aidan D., Lyng, Fiona M., Tapio, Soile, Marchetti, Luca, Saran, Anna, Pazzaglia, Simonetta, Mancuso, Mariateresa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323333/ https://www.ncbi.nlm.nih.gov/pubmed/35884524 http://dx.doi.org/10.3390/cancers14143463

Ejemplares similares

Out-of-Field Hippocampus from Partial-Body Irradiated Mice Displays Changes in Multi-Omics Profile and Defects in Neurogenesis
por: Pazzaglia, Simonetta, et al.
Publicado: (2021)

Phenotypic and Functional Characteristics of Exosomes Derived from Irradiated Mouse Organs and Their Role in the Mechanisms Driving Non-Targeted Effects
por: Tuncay Cagatay, Seda, et al.
Publicado: (2020)

Micro-RNA and Proteomic Profiles of Plasma-Derived Exosomes from Irradiated Mice Reveal Molecular Changes Preventing Apoptosis in Neonatal Cerebellum
por: Pazzaglia, Simonetta, et al.
Publicado: (2022)

Nanog-driven cell-reprogramming and self-renewal maintenance in Ptch1(+/−) granule cell precursors after radiation injury
por: Tanno, Barbara, et al.
Publicado: (2017)

Acceleration of atherogenesis in ApoE(−/−) mice exposed to acute or low-dose-rate ionizing radiation
por: Mancuso, Mariateresa, et al.
Publicado: (2015)

Synthetic lethal genetic interactions between Rad54 and PARP-1 in mouse development and oncogenesis
por: Tanori, Mirella, et al.
Publicado: (2016)

Tomato Bushy Stunt Virus Nanoparticles as a Platform for Drug Delivery to Shh-Dependent Medulloblastoma
por: Lico, Chiara, et al.
Publicado: (2021)

Ex vivo miRNome analysis in Ptch1(+/−) cerebellum granule cells reveals a subset of miRNAs involved in radiation-induced medulloblastoma
por: Tanno, Barbara, et al.
Publicado: (2016)

Neurocognitive Decline Following Radiotherapy: Mechanisms and Therapeutic Implications
por: Pazzaglia, Simonetta, et al.
Publicado: (2020)

Transgenerational inheritance of enhanced susceptibility to radiation-induced medulloblastoma in newborn Ptch1(+/−) mice after paternal irradiation
por: Paris, Lorena, et al.
Publicado: (2015)

Developmental and oncogenic effects of Insulin-like Growth Factor-I in Ptc1(+/- )mouse cerebellum
por: Tanori, Mirella, et al.
Publicado: (2010)

Hyperacetylation of Cardiac Mitochondrial Proteins Is Associated with Metabolic Impairment and Sirtuin Downregulation after Chronic Total Body Irradiation of ApoE (-/-) Mice
por: Barjaktarovic, Zarko, et al.
Publicado: (2019)

The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation
por: Kempf, Stefan J, et al.
Publicado: (2014)

Peptide-Functionalized and Drug-Loaded Tomato Bushy Stunt Virus Nanoparticles Counteract Tumor Growth in a Mouse Model of Shh-Dependent Medulloblastoma
por: Marchetti, Luca, et al.
Publicado: (2023)

Gut-brain axis: does intestinal inflammation affect hippocampal neurogenesis and medulloblastoma development?
por: Casciati, Arianna, et al.
Publicado: (2023)

Human Medulloblastoma Cell Lines: Investigating on Cancer Stem Cell-Like Phenotype
por: Casciati, Arianna, et al.
Publicado: (2020)

The Lsktm1 Locus Modulates Lung and Skin Tumorigenesis in the Mouse
por: Galvan, Antonella, et al.
Publicado: (2012)

Age-related effects of X-ray irradiation on mouse hippocampus
por: Casciati, Arianna, et al.
Publicado: (2016)

N(6)-isopentenyladenosine and analogs activate the NRF2-mediated antioxidant response
por: Dassano, Alice, et al.
Publicado: (2014)

Characterization of Early and Late Damage in a Mouse Model of Pelvic Radiation Disease
por: Vitali, Roberta, et al.
Publicado: (2023)

Late Effects of Chronic Low Dose Rate Total Body Irradiation on the Heart Proteome of ApoE(−/−) Mice Resemble Premature Cardiac Ageing
por: Azimzadeh, Omid, et al.
Publicado: (2023)

Correction: Discrimination of breast cancer from benign tumours using Raman spectroscopy
por: Lyng, Fiona M., et al.
Publicado: (2019)

Discrimination of breast cancer from benign tumours using Raman spectroscopy
por: Lyng, Fiona M., et al.
Publicado: (2019)

Long-Term Effects of Ionizing Radiation on the Hippocampus: Linking Effects of the Sonic Hedgehog Pathway Activation with Radiation Response
por: Antonelli, Francesca, et al.
Publicado: (2021)

Monitoring Radiotherapeutic Response in Prostate Cancer Patients Using High Throughput FTIR Spectroscopy of Liquid Biopsies
por: Medipally, Dinesh K.R., et al.
Publicado: (2019)

The relevance of prelamin A and RAD51 as molecular biomarkers in cervical cancer
por: Leonardi, Simona, et al.
Publicado: (2017)

Application of Advanced Non-Linear Spectral Decomposition and Regression Methods for Spectroscopic Analysis of Targeted and Non-Targeted Irradiation Effects in an In-Vitro Model
por: Slattery, Ciara, et al.
Publicado: (2022)

Alterations in Morphology and Adult Neurogenesis in the Dentate Gyrus of Patched1 Heterozygous Mice
por: Antonelli, Francesca, et al.
Publicado: (2018)

Vibrational spectroscopy of liquid biopsies for prostate cancer diagnosis
por: Medipally, Dinesh K. R., et al.
Publicado: (2020)

A systems radiation biology approach to unravel the role of chronic low-dose-rate gamma-irradiation in inducing premature senescence in endothelial cells
por: Babini, Gabriele, et al.
Publicado: (2022)

Gut–Brain Axis: Insights from Hippocampal Neurogenesis and Brain Tumor Development in a Mouse Model of Experimental Colitis Induced by Dextran Sodium Sulfate
por: Vitali, Roberta, et al.
Publicado: (2022)

Long-term consequences of in utero irradiated mice indicate proteomic changes in synaptic plasticity related signalling
por: Kempf, Stefan J., et al.
Publicado: (2015)

Pathology and biology of radiation-induced cardiac disease
por: Tapio, Soile
Publicado: (2016)

In-Utero Low-Dose Irradiation Leads to Persistent Alterations in the Mouse Heart Proteome
por: Bakshi, Mayur V., et al.
Publicado: (2016)

Biodistribution and acute toxicity of a nanofluid containing manganese iron oxide nanoparticles produced by a mechanochemical process
por: Bellusci, Mariangela, et al.
Publicado: (2014)

Raman spectroscopic detection of high-grade cervical cytology: Using morphologically normal appearing cells
por: Duraipandian, Shiyamala, et al.
Publicado: (2018)

Brain Radiation Information Data Exchange (BRIDE): integration of experimental data from low-dose ionising radiation research for pathway discovery
por: Karapiperis, Christos, et al.
Publicado: (2016)

Activation of PPARα by Fenofibrate Attenuates the Effect of Local Heart High Dose Irradiation on the Mouse Cardiac Proteome
por: Azimzadeh, Omid, et al.
Publicado: (2021)

Data-Independent Acquisition Proteomics Reveals Long-Term Biomarkers in the Serum of C57BL/6J Mice Following Local High-Dose Heart Irradiation
por: Azimzadeh, Omid, et al.
Publicado: (2021)

Exposure of the SH-SY5Y Human Neuroblastoma Cells to 50-Hz Magnetic Field: Comparison Between Two-Dimensional (2D) and Three-Dimensional (3D) In Vitro Cultures
por: Consales, Claudia, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_p7q144frifmsk70g0eftsfkcok