Cargando…

Fatty Acid Composition of Milk from Mothers with Normal Weight, Obesity, or Gestational Diabetes

Gestation and the neonatal period are crucial periods in infant development. Many components of breast milk, including fatty acids, play an important role in strengthening the immune system. The aim of our research was to evaluate the fatty acid profiles of milk from 69 mothers, including subjects h...

Descripción completa

Detalles Bibliográficos
Autores principales: Simon Sarkadi, Livia, Zhang, Miaomiao, Muránszky, Géza, Vass, Réka Anna, Matsyura, Oksana, Benes, Eszter, Vari, Sandor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323340/
https://www.ncbi.nlm.nih.gov/pubmed/35888181
http://dx.doi.org/10.3390/life12071093
_version_ 1784756526519418880
author Simon Sarkadi, Livia
Zhang, Miaomiao
Muránszky, Géza
Vass, Réka Anna
Matsyura, Oksana
Benes, Eszter
Vari, Sandor G.
author_facet Simon Sarkadi, Livia
Zhang, Miaomiao
Muránszky, Géza
Vass, Réka Anna
Matsyura, Oksana
Benes, Eszter
Vari, Sandor G.
author_sort Simon Sarkadi, Livia
collection PubMed
description Gestation and the neonatal period are crucial periods in infant development. Many components of breast milk, including fatty acids, play an important role in strengthening the immune system. The aim of our research was to evaluate the fatty acid profiles of milk from 69 mothers, including subjects having a normal weight, obesity, or gestational diabetes. For the analyses, we used gas chromatography (GC) with flame ionization detection (FID) and GC coupled with mass spectrometry (GC/MS). The main fatty acids found in breast milk were palmitic acid (C16:0; 26–28%), linoleic acid (C18:2; 23–28%), and α-linolenic acid linoleic acid (C18:3; 15–17%), followed by myristic acid (C14:0; 5–8%), lauric acid (C12:0; 4–6%) and stearic acid (C18:0; 4–5%). The average breakdown of fatty acids was 50% saturated, 44% polyunsaturated, and 6% monounsaturated. Breast milk samples were classified using principal component analysis and linear discriminant analysis. Results showed that milk from the two major groups of obese and normal body mass index (BMI) could be distinguished with an accuracy of 89.66%. Breast milk samples of Hungarian and Ukrainian mothers showed significant differences based on the fatty acid composition, which variations are attributable to the mothers’ dietary habits.
format Online
Article
Text
id pubmed-9323340
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-93233402022-07-27 Fatty Acid Composition of Milk from Mothers with Normal Weight, Obesity, or Gestational Diabetes Simon Sarkadi, Livia Zhang, Miaomiao Muránszky, Géza Vass, Réka Anna Matsyura, Oksana Benes, Eszter Vari, Sandor G. Life (Basel) Article Gestation and the neonatal period are crucial periods in infant development. Many components of breast milk, including fatty acids, play an important role in strengthening the immune system. The aim of our research was to evaluate the fatty acid profiles of milk from 69 mothers, including subjects having a normal weight, obesity, or gestational diabetes. For the analyses, we used gas chromatography (GC) with flame ionization detection (FID) and GC coupled with mass spectrometry (GC/MS). The main fatty acids found in breast milk were palmitic acid (C16:0; 26–28%), linoleic acid (C18:2; 23–28%), and α-linolenic acid linoleic acid (C18:3; 15–17%), followed by myristic acid (C14:0; 5–8%), lauric acid (C12:0; 4–6%) and stearic acid (C18:0; 4–5%). The average breakdown of fatty acids was 50% saturated, 44% polyunsaturated, and 6% monounsaturated. Breast milk samples were classified using principal component analysis and linear discriminant analysis. Results showed that milk from the two major groups of obese and normal body mass index (BMI) could be distinguished with an accuracy of 89.66%. Breast milk samples of Hungarian and Ukrainian mothers showed significant differences based on the fatty acid composition, which variations are attributable to the mothers’ dietary habits. MDPI 2022-07-21 /pmc/articles/PMC9323340/ /pubmed/35888181 http://dx.doi.org/10.3390/life12071093 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Simon Sarkadi, Livia
Zhang, Miaomiao
Muránszky, Géza
Vass, Réka Anna
Matsyura, Oksana
Benes, Eszter
Vari, Sandor G.
Fatty Acid Composition of Milk from Mothers with Normal Weight, Obesity, or Gestational Diabetes
title Fatty Acid Composition of Milk from Mothers with Normal Weight, Obesity, or Gestational Diabetes
title_full Fatty Acid Composition of Milk from Mothers with Normal Weight, Obesity, or Gestational Diabetes
title_fullStr Fatty Acid Composition of Milk from Mothers with Normal Weight, Obesity, or Gestational Diabetes
title_full_unstemmed Fatty Acid Composition of Milk from Mothers with Normal Weight, Obesity, or Gestational Diabetes
title_short Fatty Acid Composition of Milk from Mothers with Normal Weight, Obesity, or Gestational Diabetes
title_sort fatty acid composition of milk from mothers with normal weight, obesity, or gestational diabetes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323340/
https://www.ncbi.nlm.nih.gov/pubmed/35888181
http://dx.doi.org/10.3390/life12071093
work_keys_str_mv AT simonsarkadilivia fattyacidcompositionofmilkfrommotherswithnormalweightobesityorgestationaldiabetes
AT zhangmiaomiao fattyacidcompositionofmilkfrommotherswithnormalweightobesityorgestationaldiabetes
AT muranszkygeza fattyacidcompositionofmilkfrommotherswithnormalweightobesityorgestationaldiabetes
AT vassrekaanna fattyacidcompositionofmilkfrommotherswithnormalweightobesityorgestationaldiabetes
AT matsyuraoksana fattyacidcompositionofmilkfrommotherswithnormalweightobesityorgestationaldiabetes
AT beneseszter fattyacidcompositionofmilkfrommotherswithnormalweightobesityorgestationaldiabetes
AT varisandorg fattyacidcompositionofmilkfrommotherswithnormalweightobesityorgestationaldiabetes