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Fusion Proteins CLD and CLDmut Demonstrate Potent and Broad Neutralizing Activity against HIV-1

HIV-1 envelope glycoprotein (Env) interacts with cellular receptors and mediates virus entry into target cells. Blocking Env-receptor interactions represents an effective interventional strategy for developing HIV-1 entry inhibitors. We previously designed a panel of CD4-linker-DC-SIGN (CLD) constru...

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Detalles Bibliográficos
Autores principales: Fu, Ming, Xiao, Yingying, Du, Tao, Hu, Huimin, Ni, Fengfeng, Hu, Kai, Hu, Qinxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323411/
https://www.ncbi.nlm.nih.gov/pubmed/35891347
http://dx.doi.org/10.3390/v14071365

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