Alpha‐Synuclein is Involved in DYT1 Dystonia Striatal Synaptic Dysfunction

BACKGROUND: The neuronal protein alpha‐synuclein (α‐Syn) is crucially involved in Parkinson's disease pathophysiology. Intriguingly, torsinA (TA), the protein causative of DYT1 dystonia, has been found to accumulate in Lewy bodies and to interact with α‐Syn. Both proteins act as molecular chape...

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Detalles Bibliográficos
Autores principales: Ponterio, Giulia, Faustini, Gaia, El Atiallah, Ilham, Sciamanna, Giuseppe, Meringolo, Maria, Tassone, Annalisa, Imbriani, Paola, Cerri, Silvia, Martella, Giuseppina, Bonsi, Paola, Bellucci, Arianna, Pisani, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Regular Issue Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323501/
https://www.ncbi.nlm.nih.gov/pubmed/35420219
http://dx.doi.org/10.1002/mds.29024

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