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Mass Spectrometry-Based Quantification of the Antigens in Aluminum Hydroxide-Adjuvanted Diphtheria-Tetanus-Acellular-Pertussis Combination Vaccines

Vaccines undergo stringent batch-release testing, most often including in-vivo assays for potency. For combination vaccines, such as diphtheria-tetanus-pertussis (DTaP), chemical modification induced by formaldehyde inactivation, as well as adsorption to aluminum-based adjuvants, complicates antigen...

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Detalles Bibliográficos
Autores principales:	van der Maas, Larissa, Danial, Maarten, Kersten, Gideon F. A., Metz, Bernard, Meiring, Hugo D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323524/ https://www.ncbi.nlm.nih.gov/pubmed/35891242 http://dx.doi.org/10.3390/vaccines10071078

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