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Cardiac Rhabdoid Tumor—A Rare Foe—Case Report and Literature Review

Intracardiac masses are unusual findings in infants, and most of them are benign. Nevertheless, they may be associated with a significant degree of hemodynamic instability and/or arrhythmias. Malignant tumors of the heart rarely occur in children. Rhabdoid tumors are aggressive tumors with a dismal...

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Autores principales: Luca, Alina Costina, Miron, Ingrith Crenguța, Cojocaru, Elena, Țarcă, Elena, Curpan, Alexandrina-Stefania, Mihăila, Doina, Mihaela Trandafir, Laura, Iordache, Alin-Constantin, Lupu, Vasile-Valeriu, Tazelaar, Henry D., Pădureț, Ioana Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323533/
https://www.ncbi.nlm.nih.gov/pubmed/35883926
http://dx.doi.org/10.3390/children9070942
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author Luca, Alina Costina
Miron, Ingrith Crenguța
Cojocaru, Elena
Țarcă, Elena
Curpan, Alexandrina-Stefania
Mihăila, Doina
Mihaela Trandafir, Laura
Iordache, Alin-Constantin
Lupu, Vasile-Valeriu
Tazelaar, Henry D.
Pădureț, Ioana Alexandra
author_facet Luca, Alina Costina
Miron, Ingrith Crenguța
Cojocaru, Elena
Țarcă, Elena
Curpan, Alexandrina-Stefania
Mihăila, Doina
Mihaela Trandafir, Laura
Iordache, Alin-Constantin
Lupu, Vasile-Valeriu
Tazelaar, Henry D.
Pădureț, Ioana Alexandra
author_sort Luca, Alina Costina
collection PubMed
description Intracardiac masses are unusual findings in infants, and most of them are benign. Nevertheless, they may be associated with a significant degree of hemodynamic instability and/or arrhythmias. Malignant tumors of the heart rarely occur in children. Rhabdoid tumors are aggressive tumors with a dismal prognosis even when diagnosed early. Although rhabdomyomas are common cardiac tumors in infants, they are mostly benign. The most common sites of involvement are the kidneys and central nervous system, but soft tissues, lungs, and ovaries may also be affected. The diagnosis can be challenging, particularly in sites where they do not usually occur. In the present paper, we report the case of a 2-year-old boy diagnosed with cardiac rhabdoid tumor highlighting the importance of molecular studies and recent genetic discoveries with the purpose of improving the management of such cases. The aim of this educational case report and literature review is to raise awareness of cardiac masses in children and to point out diagnostic hints toward a cardiac tumor on various imaging modalities. Given the rarity of all tumors involving the heart and the lack of symptom specificity, a high degree of suspicion is needed to arrive at the correct diagnosis.
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spelling pubmed-93235332022-07-27 Cardiac Rhabdoid Tumor—A Rare Foe—Case Report and Literature Review Luca, Alina Costina Miron, Ingrith Crenguța Cojocaru, Elena Țarcă, Elena Curpan, Alexandrina-Stefania Mihăila, Doina Mihaela Trandafir, Laura Iordache, Alin-Constantin Lupu, Vasile-Valeriu Tazelaar, Henry D. Pădureț, Ioana Alexandra Children (Basel) Case Report Intracardiac masses are unusual findings in infants, and most of them are benign. Nevertheless, they may be associated with a significant degree of hemodynamic instability and/or arrhythmias. Malignant tumors of the heart rarely occur in children. Rhabdoid tumors are aggressive tumors with a dismal prognosis even when diagnosed early. Although rhabdomyomas are common cardiac tumors in infants, they are mostly benign. The most common sites of involvement are the kidneys and central nervous system, but soft tissues, lungs, and ovaries may also be affected. The diagnosis can be challenging, particularly in sites where they do not usually occur. In the present paper, we report the case of a 2-year-old boy diagnosed with cardiac rhabdoid tumor highlighting the importance of molecular studies and recent genetic discoveries with the purpose of improving the management of such cases. The aim of this educational case report and literature review is to raise awareness of cardiac masses in children and to point out diagnostic hints toward a cardiac tumor on various imaging modalities. Given the rarity of all tumors involving the heart and the lack of symptom specificity, a high degree of suspicion is needed to arrive at the correct diagnosis. MDPI 2022-06-23 /pmc/articles/PMC9323533/ /pubmed/35883926 http://dx.doi.org/10.3390/children9070942 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Luca, Alina Costina
Miron, Ingrith Crenguța
Cojocaru, Elena
Țarcă, Elena
Curpan, Alexandrina-Stefania
Mihăila, Doina
Mihaela Trandafir, Laura
Iordache, Alin-Constantin
Lupu, Vasile-Valeriu
Tazelaar, Henry D.
Pădureț, Ioana Alexandra
Cardiac Rhabdoid Tumor—A Rare Foe—Case Report and Literature Review
title Cardiac Rhabdoid Tumor—A Rare Foe—Case Report and Literature Review
title_full Cardiac Rhabdoid Tumor—A Rare Foe—Case Report and Literature Review
title_fullStr Cardiac Rhabdoid Tumor—A Rare Foe—Case Report and Literature Review
title_full_unstemmed Cardiac Rhabdoid Tumor—A Rare Foe—Case Report and Literature Review
title_short Cardiac Rhabdoid Tumor—A Rare Foe—Case Report and Literature Review
title_sort cardiac rhabdoid tumor—a rare foe—case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323533/
https://www.ncbi.nlm.nih.gov/pubmed/35883926
http://dx.doi.org/10.3390/children9070942
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