Light-Induced Activation of a Specific Type-5 Metabotropic Glutamate Receptor Antagonist in the Ventrobasal Thalamus Causes Analgesia in a Mouse Model of Breakthrough Cancer Pain

Breakthrough cancer pain (BTcP) refers to a sudden and transient exacerbation of pain, which develops in patients treated with opioid analgesics. Fast-onset analgesia is required for the treatment of BTcP. Light-activated drugs offer a novel potential strategy for the rapid control of pain without t...

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Detalles Bibliográficos
Autores principales: Notartomaso, Serena, Antenucci, Nico, Liberatore, Francesca, Mascio, Giada, Boccadamo Pompili, Stefano Vito, Font, Joan, Scioli, Mariarosaria, Luongo, Livio, Arcella, Antonietta, Gradini, Roberto, Llebaria, Amadeu, Nicoletti, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323585/
https://www.ncbi.nlm.nih.gov/pubmed/35887364
http://dx.doi.org/10.3390/ijms23148018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323585/
https://www.ncbi.nlm.nih.gov/pubmed/35887364
http://dx.doi.org/10.3390/ijms23148018

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