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Short-Interval, Low-Dose Peptide Receptor Radionuclide Therapy in Combination with PD-1 Checkpoint Immunotherapy Induces Remission in Immunocompromised Patients with Metastatic Merkel Cell Carcinoma

Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer of the elderly, with high metastatic potential and poor prognosis. In particular, the primary resistance to immune checkpoint inhibitors (ICI) in metastatic (m)MCC patients represents a challenge not yet met by any efficient treatment modal...

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Detalles Bibliográficos
Autores principales: Aicher, Alexandra, Sindrilaru, Anca, Crisan, Diana, Thaiss, Wolfgang, Steinacker, Jochen, Beer, Meinrad, Wiegel, Thomas, Scharffetter-Kochanek, Karin, Beer, Ambros J., Prasad, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323617/
https://www.ncbi.nlm.nih.gov/pubmed/35890361
http://dx.doi.org/10.3390/pharmaceutics14071466