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TAVR for All? The Surgical Perspective

In spite of the noninferiority of transcatheter aortic valve replacement (TAVR) in high- and intermediate-risk patients, there are still obstacles that need to be overcome before the procedure is further expanded and clinically integrated. The lack of evidence on the long-term durability of the biop...

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Detalles Bibliográficos
Autores principales: Zhang, Xiling, Puehler, Thomas, Frank, Derk, Sathananthan, Janarthanan, Sellers, Stephanie, Meier, David, Both, Marcus, Blanke, Philipp, Seoudy, Hatim, Saad, Mohammed, Müller, Oliver J., Sondergaard, Lars, Lutter, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323639/
https://www.ncbi.nlm.nih.gov/pubmed/35877585
http://dx.doi.org/10.3390/jcdd9070223
Descripción
Sumario:In spite of the noninferiority of transcatheter aortic valve replacement (TAVR) in high- and intermediate-risk patients, there are still obstacles that need to be overcome before the procedure is further expanded and clinically integrated. The lack of evidence on the long-term durability of the bioprostheses used for TAVR remains of particular concern. In addition, surgery may be preferred over TAVR in patients with bicuspid aortic valve (BAV) or with concomitant pathologies such as other valve diseases (mitral regurgitation/tricuspid regurgitation), aortopathy, and coronary artery disease. In this review, we discuss and summarize relevant data from clinical trials, current trends, and remaining obstacles, and provide our perspective on the indications for the expansion of TAVR.