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Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy

Central serous chorioretinopathy (CSC) is a common chorioretinal disorder. It has been postulated that impaired retinal pigment epithelium and hyperpermeability of the choriocapillaris may be involved in the development of CSC, but the exact pathomechanism has not been established. We report an unus...

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Autores principales: Chrząszcz, Michał, Mackiewicz, Natalia, Pociej-Marciak, Weronika, Romanowska-Dixon, Bożena, Kubicka-Trząska, Agnieszka, Gawęcki, Maciej, Karska-Basta, Izabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323662/
https://www.ncbi.nlm.nih.gov/pubmed/35888581
http://dx.doi.org/10.3390/medicina58070862
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author Chrząszcz, Michał
Mackiewicz, Natalia
Pociej-Marciak, Weronika
Romanowska-Dixon, Bożena
Kubicka-Trząska, Agnieszka
Gawęcki, Maciej
Karska-Basta, Izabella
author_facet Chrząszcz, Michał
Mackiewicz, Natalia
Pociej-Marciak, Weronika
Romanowska-Dixon, Bożena
Kubicka-Trząska, Agnieszka
Gawęcki, Maciej
Karska-Basta, Izabella
author_sort Chrząszcz, Michał
collection PubMed
description Central serous chorioretinopathy (CSC) is a common chorioretinal disorder. It has been postulated that impaired retinal pigment epithelium and hyperpermeability of the choriocapillaris may be involved in the development of CSC, but the exact pathomechanism has not been established. We report an unusual case of a middle-aged man who developed CSC after triamcinolone acetonide injection for macular edema. Edema developed as a late complication of radiation retinopathy after brachytherapy for childhood retinoblastoma. Steroid treatment is an important risk factor for CSC, but the underlying causative mechanisms have not been fully elucidated. It is important to increase the awareness of this link among clinicians who prescribe exogenous corticosteroids, irrespective of the route of administration.
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spelling pubmed-93236622022-07-27 Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy Chrząszcz, Michał Mackiewicz, Natalia Pociej-Marciak, Weronika Romanowska-Dixon, Bożena Kubicka-Trząska, Agnieszka Gawęcki, Maciej Karska-Basta, Izabella Medicina (Kaunas) Case Report Central serous chorioretinopathy (CSC) is a common chorioretinal disorder. It has been postulated that impaired retinal pigment epithelium and hyperpermeability of the choriocapillaris may be involved in the development of CSC, but the exact pathomechanism has not been established. We report an unusual case of a middle-aged man who developed CSC after triamcinolone acetonide injection for macular edema. Edema developed as a late complication of radiation retinopathy after brachytherapy for childhood retinoblastoma. Steroid treatment is an important risk factor for CSC, but the underlying causative mechanisms have not been fully elucidated. It is important to increase the awareness of this link among clinicians who prescribe exogenous corticosteroids, irrespective of the route of administration. MDPI 2022-06-28 /pmc/articles/PMC9323662/ /pubmed/35888581 http://dx.doi.org/10.3390/medicina58070862 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Chrząszcz, Michał
Mackiewicz, Natalia
Pociej-Marciak, Weronika
Romanowska-Dixon, Bożena
Kubicka-Trząska, Agnieszka
Gawęcki, Maciej
Karska-Basta, Izabella
Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy
title Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy
title_full Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy
title_fullStr Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy
title_full_unstemmed Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy
title_short Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy
title_sort diagnostic and therapeutic challenges in a patient with radiation retinopathy complicated by corticosteroid-induced central serous chorioretinopathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323662/
https://www.ncbi.nlm.nih.gov/pubmed/35888581
http://dx.doi.org/10.3390/medicina58070862
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