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Triazole Derivatives Target 14α–Demethylase (LDM) Enzyme in Candida albicans Causing Ergosterol Biosynthesis Inhibition

Candida albicans is the most dominant and prevalent cause of fungal infections in humans. Azoles are considered as first-line drugs for the treatment of these infections. However, their prolonged and insistent use has led to multidrug resistance and treatment failures. To overcome this, modification...

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Detalles Bibliográficos
Autores principales:	Rather, Irfan A., Sabir, Jamal S. M., Asseri, Amer H., Wani, Mohmmad Younus, Ahmad, Aijaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323696/ https://www.ncbi.nlm.nih.gov/pubmed/35887444 http://dx.doi.org/10.3390/jof8070688

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