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The TRPC1 Channel Forms a PI3K/CaM Complex and Regulates Pancreatic Ductal Adenocarcinoma Cell Proliferation in a Ca(2+)-Independent Manner

Dysregulation of the transient receptor canonical ion channel (TRPC1) has been found in several cancer types, yet the underlying molecular mechanisms through which TRPC1 impacts pancreatic ductal adenocarcinoma (PDAC) cell proliferation are incompletely understood. Here, we found that TRPC1 is upreg...

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Detalles Bibliográficos
Autores principales: Schnipper, Julie, Kouba, Sana, Hague, Frédéric, Girault, Alban, Rybarczyk, Pierre, Telliez, Marie-Sophie, Guénin, Stéphanie, Tebbakha, Riad, Sevestre, Henri, Ahidouch, Ahmed, Pedersen, Stine Falsig, Ouadid-Ahidouch, Halima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323718/
https://www.ncbi.nlm.nih.gov/pubmed/35887266
http://dx.doi.org/10.3390/ijms23147923

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