Cargando…
The TRPC1 Channel Forms a PI3K/CaM Complex and Regulates Pancreatic Ductal Adenocarcinoma Cell Proliferation in a Ca(2+)-Independent Manner
Dysregulation of the transient receptor canonical ion channel (TRPC1) has been found in several cancer types, yet the underlying molecular mechanisms through which TRPC1 impacts pancreatic ductal adenocarcinoma (PDAC) cell proliferation are incompletely understood. Here, we found that TRPC1 is upreg...
Autores principales: | Schnipper, Julie, Kouba, Sana, Hague, Frédéric, Girault, Alban, Rybarczyk, Pierre, Telliez, Marie-Sophie, Guénin, Stéphanie, Tebbakha, Riad, Sevestre, Henri, Ahidouch, Ahmed, Pedersen, Stine Falsig, Ouadid-Ahidouch, Halima |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323718/ https://www.ncbi.nlm.nih.gov/pubmed/35887266 http://dx.doi.org/10.3390/ijms23147923 |
Ejemplares similares
-
Acid Adaptation Promotes TRPC1 Plasma Membrane Localization Leading to Pancreatic Ductal Adenocarcinoma Cell Proliferation and Migration through Ca(2+) Entry and Interaction with PI3K/CaM
por: Schnipper, Julie, et al.
Publicado: (2022) -
Crosstalk between Ca(2+) Signaling and Cancer Stemness: The Link to Cisplatin Resistance
por: Kouba, Sana, et al.
Publicado: (2022) -
Original association of ion transporters mediates the ECM-induced breast cancer cell survival: Kv10.1-Orai1-SPCA2 partnership
por: Peretti, Marta, et al.
Publicado: (2019) -
Expression of TRPC6 channels in human epithelial breast cancer cells
por: Guilbert, Arnaud, et al.
Publicado: (2008) -
Orai3 is a predictive marker of metastasis and survival in resectable lung adenocarcinoma
por: Benzerdjeb, Nazim, et al.
Publicado: (2016)