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Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis

Lysine specific demethylase 1 (LSD1; also known as KDM1A), is an epigenetic modulator that modifies the histone methylation status. KDM1A forms a part of protein complexes that regulate the expression of genes involved in the onset and progression of diseases such as cancer, central nervous system (...

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Detalles Bibliográficos
Autores principales:	Cavalcanti, Fernando, Gonzalez-Rey, Elena, Delgado, Mario, Falo, Clara P., Mestre, Leyre, Guaza, Carmen, O’Valle, Francisco, Lufino, Michele M. P., Xaus, Jordi, Mascaró, Cristina, Lunardi, Serena, Sacilotto, Natalia, Dessanti, Paola, Rotllant, David, Navarro, Xavier, Herrando-Grabulosa, Mireia, Buesa, Carlos, Maes, Tamara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323733/ https://www.ncbi.nlm.nih.gov/pubmed/35890315 http://dx.doi.org/10.3390/pharmaceutics14071420

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