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In Silico Analysis of PORD Mutations on the 3D Structure of P450 Oxidoreductase

Cytochrome P450 oxidoreductase (POR) is a membrane-bound flavoprotein that helps in transferring electrons from its NADPH domain to all cytochrome P450 (CYP450) enzymes. Mutations in the POR gene could severely affect the metabolism of steroid hormones and the development of skeletal muscles, a cond...

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Detalles Bibliográficos
Autores principales: Nurhafizuddin, Muhammad, Azizi, Aziemah, Ming, Long Chiau, Shafqat, Naeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323898/
https://www.ncbi.nlm.nih.gov/pubmed/35889519
http://dx.doi.org/10.3390/molecules27144646