CYP3A5*3 and SLCO1B1 c.521T>C Polymorphisms Influence the Pharmacokinetics of Atorvastatin and 2-Hydroxy Atorvastatin

There is a large variability in individual responses to atorvastatin administration. This study assessed the pharmacogenetic effects of solute carrier organic anion transporter family member 1B1 (SLCO1B1, c.388A>G and c.521T>C) and cytochrome P450 3A5 (CYP3A5, CYP3A5*3) genetic polymorphisms o...

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Detalles Bibliográficos
Autores principales: Park, Jin-Woo, Kim, Jong-Min, Lee, Hwa-Young, Noh, Jihyeon, Kim, Kyoung-Ah, Park, Ji-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323915/
https://www.ncbi.nlm.nih.gov/pubmed/35890386
http://dx.doi.org/10.3390/pharmaceutics14071491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323915/
https://www.ncbi.nlm.nih.gov/pubmed/35890386
http://dx.doi.org/10.3390/pharmaceutics14071491

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