Cargando…

Preliminary Findings from the Gulf War Women’s Cohort: Reproductive and Children’s Health Outcomes among Women Veterans

Reproductive outcomes, such as preterm birth, miscarriage/stillbirth, and pre-eclampsia, are understudied in veterans, particularly among Gulf War veterans (GWVs). During deployment, women GWVs were exposed to toxicant and nontoxicant exposures that may be associated with adverse reproductive and de...

Descripción completa

Detalles Bibliográficos
Autores principales: Friedman, Alexa, Janulewicz Lloyd, Patricia A., Carlson, Jeffrey, Quinn, Emily, Keating, Dylan, Toomey, Rosemary, Heeren, Timothy, Coughlin, Steven S., Markenson, Glenn, Krengel, Maxine, Sullivan, Kimberly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323962/
https://www.ncbi.nlm.nih.gov/pubmed/35886335
http://dx.doi.org/10.3390/ijerph19148483
_version_ 1784756689520558080
author Friedman, Alexa
Janulewicz Lloyd, Patricia A.
Carlson, Jeffrey
Quinn, Emily
Keating, Dylan
Toomey, Rosemary
Heeren, Timothy
Coughlin, Steven S.
Markenson, Glenn
Krengel, Maxine
Sullivan, Kimberly
author_facet Friedman, Alexa
Janulewicz Lloyd, Patricia A.
Carlson, Jeffrey
Quinn, Emily
Keating, Dylan
Toomey, Rosemary
Heeren, Timothy
Coughlin, Steven S.
Markenson, Glenn
Krengel, Maxine
Sullivan, Kimberly
author_sort Friedman, Alexa
collection PubMed
description Reproductive outcomes, such as preterm birth, miscarriage/stillbirth, and pre-eclampsia, are understudied in veterans, particularly among Gulf War veterans (GWVs). During deployment, women GWVs were exposed to toxicant and nontoxicant exposures that may be associated with adverse reproductive and developmental outcomes. The data come from a survey of 239 participants from northeastern and southern U.S. cohorts of women veterans. The questionnaire collected information about the service history, current and past general health, reproductive and family health, demographic information, and deployment exposures. Odds ratios were computed with 95% confidence intervals between exposures in theater and reproductive/children’s health outcomes. GWVs experienced adverse reproductive outcomes: 25% had difficulty conceiving, and 31% had a pregnancy that ended in a miscarriage or stillbirth. Pregnancy complications were common among GWVs: 23% had a high-risk pregnancy, and 16% were diagnosed with pre-eclampsia. About a third of GWVs reported their children (38%) had a developmental disorder. Use of pesticide cream during deployment was associated with higher odds of all reproductive and developmental outcomes. The results demonstrate that GWVs experienced reproductive and children’s health outcomes at potentially high rates, and exploratory analyses suggest pesticide exposure as associated with higher odds of adverse reproductive outcomes. Future longitudinal studies of women veterans should prioritize examining reproductive and children’s health outcomes.
format Online
Article
Text
id pubmed-9323962
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-93239622022-07-27 Preliminary Findings from the Gulf War Women’s Cohort: Reproductive and Children’s Health Outcomes among Women Veterans Friedman, Alexa Janulewicz Lloyd, Patricia A. Carlson, Jeffrey Quinn, Emily Keating, Dylan Toomey, Rosemary Heeren, Timothy Coughlin, Steven S. Markenson, Glenn Krengel, Maxine Sullivan, Kimberly Int J Environ Res Public Health Brief Report Reproductive outcomes, such as preterm birth, miscarriage/stillbirth, and pre-eclampsia, are understudied in veterans, particularly among Gulf War veterans (GWVs). During deployment, women GWVs were exposed to toxicant and nontoxicant exposures that may be associated with adverse reproductive and developmental outcomes. The data come from a survey of 239 participants from northeastern and southern U.S. cohorts of women veterans. The questionnaire collected information about the service history, current and past general health, reproductive and family health, demographic information, and deployment exposures. Odds ratios were computed with 95% confidence intervals between exposures in theater and reproductive/children’s health outcomes. GWVs experienced adverse reproductive outcomes: 25% had difficulty conceiving, and 31% had a pregnancy that ended in a miscarriage or stillbirth. Pregnancy complications were common among GWVs: 23% had a high-risk pregnancy, and 16% were diagnosed with pre-eclampsia. About a third of GWVs reported their children (38%) had a developmental disorder. Use of pesticide cream during deployment was associated with higher odds of all reproductive and developmental outcomes. The results demonstrate that GWVs experienced reproductive and children’s health outcomes at potentially high rates, and exploratory analyses suggest pesticide exposure as associated with higher odds of adverse reproductive outcomes. Future longitudinal studies of women veterans should prioritize examining reproductive and children’s health outcomes. MDPI 2022-07-11 /pmc/articles/PMC9323962/ /pubmed/35886335 http://dx.doi.org/10.3390/ijerph19148483 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Friedman, Alexa
Janulewicz Lloyd, Patricia A.
Carlson, Jeffrey
Quinn, Emily
Keating, Dylan
Toomey, Rosemary
Heeren, Timothy
Coughlin, Steven S.
Markenson, Glenn
Krengel, Maxine
Sullivan, Kimberly
Preliminary Findings from the Gulf War Women’s Cohort: Reproductive and Children’s Health Outcomes among Women Veterans
title Preliminary Findings from the Gulf War Women’s Cohort: Reproductive and Children’s Health Outcomes among Women Veterans
title_full Preliminary Findings from the Gulf War Women’s Cohort: Reproductive and Children’s Health Outcomes among Women Veterans
title_fullStr Preliminary Findings from the Gulf War Women’s Cohort: Reproductive and Children’s Health Outcomes among Women Veterans
title_full_unstemmed Preliminary Findings from the Gulf War Women’s Cohort: Reproductive and Children’s Health Outcomes among Women Veterans
title_short Preliminary Findings from the Gulf War Women’s Cohort: Reproductive and Children’s Health Outcomes among Women Veterans
title_sort preliminary findings from the gulf war women’s cohort: reproductive and children’s health outcomes among women veterans
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323962/
https://www.ncbi.nlm.nih.gov/pubmed/35886335
http://dx.doi.org/10.3390/ijerph19148483
work_keys_str_mv AT friedmanalexa preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans
AT janulewiczlloydpatriciaa preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans
AT carlsonjeffrey preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans
AT quinnemily preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans
AT keatingdylan preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans
AT toomeyrosemary preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans
AT heerentimothy preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans
AT coughlinstevens preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans
AT markensonglenn preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans
AT krengelmaxine preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans
AT sullivankimberly preliminaryfindingsfromthegulfwarwomenscohortreproductiveandchildrenshealthoutcomesamongwomenveterans