Co-Delivery of siRNA and Chemotherapeutic Drug Using 2C5 Antibody-Targeted Dendrimer-Based Mixed Micelles for Multidrug Resistant Cancers

Multidrug resistance (MDR) observed in tumors significantly hinders the efficacy of chemotherapy. Downregulation of efflux proteins, such as P-glycoprotein (P-gp), using small interfering RNA (siRNA) can be an effective way to minimize the resistance in tumors. In this study, monoclonal antibody 2C5...

Descripción completa

Detalles Bibliográficos
Autores principales: Yalamarty, Satya Siva Kishan, Filipczak, Nina, Li, Xiang, Pathrikar, Tanvi Vinod, Cotter, Colin, Torchilin, Vladimir P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324017/
https://www.ncbi.nlm.nih.gov/pubmed/35890364
http://dx.doi.org/10.3390/pharmaceutics14071470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324017/
https://www.ncbi.nlm.nih.gov/pubmed/35890364
http://dx.doi.org/10.3390/pharmaceutics14071470

Ejemplares similares