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Co-Delivery of siRNA and Chemotherapeutic Drug Using 2C5 Antibody-Targeted Dendrimer-Based Mixed Micelles for Multidrug Resistant Cancers

Multidrug resistance (MDR) observed in tumors significantly hinders the efficacy of chemotherapy. Downregulation of efflux proteins, such as P-glycoprotein (P-gp), using small interfering RNA (siRNA) can be an effective way to minimize the resistance in tumors. In this study, monoclonal antibody 2C5...

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Detalles Bibliográficos
Autores principales:	Yalamarty, Satya Siva Kishan, Filipczak, Nina, Li, Xiang, Pathrikar, Tanvi Vinod, Cotter, Colin, Torchilin, Vladimir P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324017/ https://www.ncbi.nlm.nih.gov/pubmed/35890364 http://dx.doi.org/10.3390/pharmaceutics14071470

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