Cargando…
Discovery of Small Molecules from Echinacea angustifolia Targeting RNA-Dependent RNA Polymerase of Japanese Encephalitis Virus
The Japanese encephalitis virus (JEV), a mosquito-borne flavivirus that causes viral encephalitis leading to neural damage, is a major threat in most Asian countries. The RNA-dependent RNA polymerase (RdRp) present in the viral genome is the key component for genome replication, making it an attract...
Autores principales: | Yadav, Pardeep, El-Kafrawy, Sherif A., El-Day, Mai M., Alghafari, Wejdan T., Faizo, Arwa A., Jha, Saurabh Kumar, Dwivedi, Vivek Dhar, Azhar, Esam I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324244/ https://www.ncbi.nlm.nih.gov/pubmed/35888042 http://dx.doi.org/10.3390/life12070952 |
Ejemplares similares
-
Mechanistic insights into the Japanese encephalitis virus RNA dependent RNA polymerase protein inhibition by bioflavonoids from Azadirachta indica
por: Dwivedi, Vivek Dhar, et al.
Publicado: (2021) -
Discovery of Bispecific Lead Compounds from Azadirachta indica against ZIKA NS2B-NS3 Protease and NS5 RNA Dependent RNA Polymerase Using Molecular Simulations
por: Kumar, Sanjay, et al.
Publicado: (2022) -
Structure-Based Identification of Natural Products as SARS-CoV-2 M(pro) Antagonist from Echinacea angustifolia Using Computational Approaches
por: Bharadwaj, Shiv, et al.
Publicado: (2021) -
Pharmacophore-Model-Based Drug Repurposing for the Identification of the Potential Inhibitors Targeting the Allosteric Site in Dengue Virus NS5 RNA-Dependent RNA Polymerase
por: Kumar, Sanjay, et al.
Publicado: (2022) -
In vitro screening of anti-viral and virucidal effects against SARS-CoV-2 by Hypericum perforatum and Echinacea
por: Bajrai, Leena Hussein, et al.
Publicado: (2022)