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Diabetic Retinopathy Detection from Fundus Images of the Eye Using Hybrid Deep Learning Features

Diabetic Retinopathy (DR) is a medical condition present in patients suffering from long-term diabetes. If a diagnosis is not carried out at an early stage, it can lead to vision impairment. High blood sugar in diabetic patients is the main source of DR. This affects the blood vessels within the ret...

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Autores principales: Butt, Muhammad Mohsin, Iskandar, D. N. F. Awang, Abdelhamid, Sherif E., Latif, Ghazanfar, Alghazo, Runna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324358/
https://www.ncbi.nlm.nih.gov/pubmed/35885512
http://dx.doi.org/10.3390/diagnostics12071607
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author Butt, Muhammad Mohsin
Iskandar, D. N. F. Awang
Abdelhamid, Sherif E.
Latif, Ghazanfar
Alghazo, Runna
author_facet Butt, Muhammad Mohsin
Iskandar, D. N. F. Awang
Abdelhamid, Sherif E.
Latif, Ghazanfar
Alghazo, Runna
author_sort Butt, Muhammad Mohsin
collection PubMed
description Diabetic Retinopathy (DR) is a medical condition present in patients suffering from long-term diabetes. If a diagnosis is not carried out at an early stage, it can lead to vision impairment. High blood sugar in diabetic patients is the main source of DR. This affects the blood vessels within the retina. Manual detection of DR is a difficult task since it can affect the retina, causing structural changes such as Microaneurysms (MAs), Exudates (EXs), Hemorrhages (HMs), and extra blood vessel growth. In this work, a hybrid technique for the detection and classification of Diabetic Retinopathy in fundus images of the eye is proposed. Transfer learning (TL) is used on pre-trained Convolutional Neural Network (CNN) models to extract features that are combined to generate a hybrid feature vector. This feature vector is passed on to various classifiers for binary and multiclass classification of fundus images. System performance is measured using various metrics and results are compared with recent approaches for DR detection. The proposed method provides significant performance improvement in DR detection for fundus images. For binary classification, the proposed modified method achieved the highest accuracy of 97.8% and 89.29% for multiclass classification.
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spelling pubmed-93243582022-07-27 Diabetic Retinopathy Detection from Fundus Images of the Eye Using Hybrid Deep Learning Features Butt, Muhammad Mohsin Iskandar, D. N. F. Awang Abdelhamid, Sherif E. Latif, Ghazanfar Alghazo, Runna Diagnostics (Basel) Article Diabetic Retinopathy (DR) is a medical condition present in patients suffering from long-term diabetes. If a diagnosis is not carried out at an early stage, it can lead to vision impairment. High blood sugar in diabetic patients is the main source of DR. This affects the blood vessels within the retina. Manual detection of DR is a difficult task since it can affect the retina, causing structural changes such as Microaneurysms (MAs), Exudates (EXs), Hemorrhages (HMs), and extra blood vessel growth. In this work, a hybrid technique for the detection and classification of Diabetic Retinopathy in fundus images of the eye is proposed. Transfer learning (TL) is used on pre-trained Convolutional Neural Network (CNN) models to extract features that are combined to generate a hybrid feature vector. This feature vector is passed on to various classifiers for binary and multiclass classification of fundus images. System performance is measured using various metrics and results are compared with recent approaches for DR detection. The proposed method provides significant performance improvement in DR detection for fundus images. For binary classification, the proposed modified method achieved the highest accuracy of 97.8% and 89.29% for multiclass classification. MDPI 2022-07-01 /pmc/articles/PMC9324358/ /pubmed/35885512 http://dx.doi.org/10.3390/diagnostics12071607 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Butt, Muhammad Mohsin
Iskandar, D. N. F. Awang
Abdelhamid, Sherif E.
Latif, Ghazanfar
Alghazo, Runna
Diabetic Retinopathy Detection from Fundus Images of the Eye Using Hybrid Deep Learning Features
title Diabetic Retinopathy Detection from Fundus Images of the Eye Using Hybrid Deep Learning Features
title_full Diabetic Retinopathy Detection from Fundus Images of the Eye Using Hybrid Deep Learning Features
title_fullStr Diabetic Retinopathy Detection from Fundus Images of the Eye Using Hybrid Deep Learning Features
title_full_unstemmed Diabetic Retinopathy Detection from Fundus Images of the Eye Using Hybrid Deep Learning Features
title_short Diabetic Retinopathy Detection from Fundus Images of the Eye Using Hybrid Deep Learning Features
title_sort diabetic retinopathy detection from fundus images of the eye using hybrid deep learning features
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324358/
https://www.ncbi.nlm.nih.gov/pubmed/35885512
http://dx.doi.org/10.3390/diagnostics12071607
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