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Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review

Viral infections are a key issue in modern medicine. SARS-CoV-2 infection confirms that we are not sufficiently prepared for these unforeseen infections. The COVID-19 pandemic has cultivated a great sense of fear and distrust in patients. If viral infections, in this case, SARS-CoV-2, overlap with a...

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Autores principales: Sur, Maria Lucia, Moldovan, Bogdan-Stefan, Mocanu, Diana, Samasca, Gabriel, Lupan, Iulia, Armat, Ionel, Harabagiu, Marin, Sur, Genel, Lazar, Calin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324372/
https://www.ncbi.nlm.nih.gov/pubmed/35888030
http://dx.doi.org/10.3390/life12070940
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author Sur, Maria Lucia
Moldovan, Bogdan-Stefan
Mocanu, Diana
Samasca, Gabriel
Lupan, Iulia
Armat, Ionel
Harabagiu, Marin
Sur, Genel
Lazar, Calin
author_facet Sur, Maria Lucia
Moldovan, Bogdan-Stefan
Mocanu, Diana
Samasca, Gabriel
Lupan, Iulia
Armat, Ionel
Harabagiu, Marin
Sur, Genel
Lazar, Calin
author_sort Sur, Maria Lucia
collection PubMed
description Viral infections are a key issue in modern medicine. SARS-CoV-2 infection confirms that we are not sufficiently prepared for these unforeseen infections. The COVID-19 pandemic has cultivated a great sense of fear and distrust in patients. If viral infections, in this case, SARS-CoV-2, overlap with another infection, the symptoms are prolonged and worsened, and complications may occur. Starting from an objective clinical finding of a patient they had in follow-up and treatment, the authors present the problems of the diseases the patient suffered from. These are described as reviews so that readers can get an idea of the clinical methods of expression and the therapeutic possibilities. Therefore, this article describes Lyme disease and post-treatment Lyme disease syndrome, SARS-CoV-2 infection, and multisystem inflammatory syndrome in children (MISC-C), as the patient suffered from an incomplete form of Kawasaki disease. During the treatment for Lyme disease, the patient also contracted the influenza type A virus. Although any of these diseases could have the potential for serious evolution, our patient still went through these infections relatively well. This can be explained by the fact that the patient had a slow immune response to the aforementioned infections, which allowed him to survive these diseases relatively easily, unlike other individuals who have an exaggerated immune response or who suffer from serious immune involvement, e.g., hepatitis B with a fulminant response. The case was presented chronologically, but at the same time, all particular infection manifestations were accurately described. For these reasons, the article is presented in the form of a review, exemplified by the case itself. Of the 52 cases of MISC-C found in the Pediatrics Clinic II of Cluj-Napoca, we present the case of a male patient who presented with Lyme disease, post-treatment Lyme disease syndrome, Kawasaki disease, and MISC-C incomplete form.
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spelling pubmed-93243722022-07-27 Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review Sur, Maria Lucia Moldovan, Bogdan-Stefan Mocanu, Diana Samasca, Gabriel Lupan, Iulia Armat, Ionel Harabagiu, Marin Sur, Genel Lazar, Calin Life (Basel) Article Viral infections are a key issue in modern medicine. SARS-CoV-2 infection confirms that we are not sufficiently prepared for these unforeseen infections. The COVID-19 pandemic has cultivated a great sense of fear and distrust in patients. If viral infections, in this case, SARS-CoV-2, overlap with another infection, the symptoms are prolonged and worsened, and complications may occur. Starting from an objective clinical finding of a patient they had in follow-up and treatment, the authors present the problems of the diseases the patient suffered from. These are described as reviews so that readers can get an idea of the clinical methods of expression and the therapeutic possibilities. Therefore, this article describes Lyme disease and post-treatment Lyme disease syndrome, SARS-CoV-2 infection, and multisystem inflammatory syndrome in children (MISC-C), as the patient suffered from an incomplete form of Kawasaki disease. During the treatment for Lyme disease, the patient also contracted the influenza type A virus. Although any of these diseases could have the potential for serious evolution, our patient still went through these infections relatively well. This can be explained by the fact that the patient had a slow immune response to the aforementioned infections, which allowed him to survive these diseases relatively easily, unlike other individuals who have an exaggerated immune response or who suffer from serious immune involvement, e.g., hepatitis B with a fulminant response. The case was presented chronologically, but at the same time, all particular infection manifestations were accurately described. For these reasons, the article is presented in the form of a review, exemplified by the case itself. Of the 52 cases of MISC-C found in the Pediatrics Clinic II of Cluj-Napoca, we present the case of a male patient who presented with Lyme disease, post-treatment Lyme disease syndrome, Kawasaki disease, and MISC-C incomplete form. MDPI 2022-06-23 /pmc/articles/PMC9324372/ /pubmed/35888030 http://dx.doi.org/10.3390/life12070940 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sur, Maria Lucia
Moldovan, Bogdan-Stefan
Mocanu, Diana
Samasca, Gabriel
Lupan, Iulia
Armat, Ionel
Harabagiu, Marin
Sur, Genel
Lazar, Calin
Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title_full Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title_fullStr Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title_full_unstemmed Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title_short Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title_sort immune responses to some viral infections that have a high evolutionary potential—a case report with literature review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324372/
https://www.ncbi.nlm.nih.gov/pubmed/35888030
http://dx.doi.org/10.3390/life12070940
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