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Biodistribution Analysis of an Anti-EGFR Antibody in the Rat Brain: Validation of CSF Microcirculation as a Viable Pathway to Circumvent the Blood-Brain Barrier for Drug Delivery

Cerebrospinal fluid (CSF) microcirculation refers to CSF flow through brain or spinal parenchyma. CSF enters the tissue along the perivascular spaces of the penetrating arteries where it mixes with the interstitial fluid circulating through the extracellular space. The potential of harnessing CSF mi...

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Detalles Bibliográficos
Autores principales:	Naseri Kouzehgarani, Ghazal, Kumar, Pankaj, Bolin, Susan E., Reilly, Edward B., Lefebvre, Didier R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324388/ https://www.ncbi.nlm.nih.gov/pubmed/35890344 http://dx.doi.org/10.3390/pharmaceutics14071441

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