The Dct(−/−) Mouse Model to Unravel Retinogenesis Misregulation in Patients with Albinism

We have recently identified DCT encoding dopachrome tautomerase (DCT) as the eighth gene for oculocutaneous albinism (OCA). Patients with loss of function of DCT suffer from eye hypopigmentation and retinal dystrophy. Here we investigate the eye phenotype in Dct(−/−) mice. We show that their retinal...

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Detalles Bibliográficos
Autores principales: Tingaud-Sequeira, Angèle, Mercier, Elina, Michaud, Vincent, Pinson, Benoît, Gazova, Ivet, Gontier, Etienne, Decoeur, Fanny, McKie, Lisa, Jackson, Ian J., Arveiler, Benoît, Javerzat, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324463/
https://www.ncbi.nlm.nih.gov/pubmed/35885947
http://dx.doi.org/10.3390/genes13071164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324463/
https://www.ncbi.nlm.nih.gov/pubmed/35885947
http://dx.doi.org/10.3390/genes13071164

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