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Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview

The dysfunctionality of the protective skin barrier in psoriasis allows easier cutaneous penetration of various contact haptens; thus, such patients can develop allergic contact hypersensitivity as a comorbidity. Both skin conditions involve T-cell-mediated mechanisms. Dermatologists and allergists...

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Detalles Bibliográficos
Autores principales: Stănescu, Ana Maria Alexandra, Cristea, Ana-Maria-Antoaneta, Bejan, Gabriel Cristian, Vieru, Mariana, Simionescu, Anca Angela, Popescu, Florin-Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324524/
https://www.ncbi.nlm.nih.gov/pubmed/35888633
http://dx.doi.org/10.3390/medicina58070914
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author Stănescu, Ana Maria Alexandra
Cristea, Ana-Maria-Antoaneta
Bejan, Gabriel Cristian
Vieru, Mariana
Simionescu, Anca Angela
Popescu, Florin-Dan
author_facet Stănescu, Ana Maria Alexandra
Cristea, Ana-Maria-Antoaneta
Bejan, Gabriel Cristian
Vieru, Mariana
Simionescu, Anca Angela
Popescu, Florin-Dan
author_sort Stănescu, Ana Maria Alexandra
collection PubMed
description The dysfunctionality of the protective skin barrier in psoriasis allows easier cutaneous penetration of various contact haptens; thus, such patients can develop allergic contact hypersensitivity as a comorbidity. Both skin conditions involve T-cell-mediated mechanisms. Dermatologists and allergists should consider assessing allergic contact cell-mediated hypersensitivity in selected psoriasis patients, especially those with palmoplantar psoriasis and who are refractory to topical treatments, and in patients with psoriasis, with or without arthritis, treated with biologics that present skin lesions clinically suggestive of contact dermatitis.
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spelling pubmed-93245242022-07-27 Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview Stănescu, Ana Maria Alexandra Cristea, Ana-Maria-Antoaneta Bejan, Gabriel Cristian Vieru, Mariana Simionescu, Anca Angela Popescu, Florin-Dan Medicina (Kaunas) Review The dysfunctionality of the protective skin barrier in psoriasis allows easier cutaneous penetration of various contact haptens; thus, such patients can develop allergic contact hypersensitivity as a comorbidity. Both skin conditions involve T-cell-mediated mechanisms. Dermatologists and allergists should consider assessing allergic contact cell-mediated hypersensitivity in selected psoriasis patients, especially those with palmoplantar psoriasis and who are refractory to topical treatments, and in patients with psoriasis, with or without arthritis, treated with biologics that present skin lesions clinically suggestive of contact dermatitis. MDPI 2022-07-09 /pmc/articles/PMC9324524/ /pubmed/35888633 http://dx.doi.org/10.3390/medicina58070914 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Stănescu, Ana Maria Alexandra
Cristea, Ana-Maria-Antoaneta
Bejan, Gabriel Cristian
Vieru, Mariana
Simionescu, Anca Angela
Popescu, Florin-Dan
Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview
title Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview
title_full Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview
title_fullStr Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview
title_full_unstemmed Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview
title_short Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview
title_sort allergic contact cell-mediated hypersensitivity in psoriasis: a narrative minireview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324524/
https://www.ncbi.nlm.nih.gov/pubmed/35888633
http://dx.doi.org/10.3390/medicina58070914
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