Cargando…

Conformational Properties and Putative Bioactive Targets for Novel Thiosemicarbazone Derivatives

The structure assignment and conformational analysis of the thiosemicarbazones, DKI21 and DKI24, were performed through homonuclear and heteronuclear 2D Nuclear Magnetic Resonance (NMR) spectroscopy (2D-COSY, 2D-NOESY, 2D-ROESY, 2D-HSQC, and 2D-HMBC) and quantum mechanics (QM) calculations, using Fu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Georgiou, Nikitas, Cheilari, Antigoni, Karta, Danai, Chontzopoulou, Eleni, Plavec, Janez, Tzeli, Demeter, Vassiliou, Stamatia, Mavromoustakos, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324535/ https://www.ncbi.nlm.nih.gov/pubmed/35889421 http://dx.doi.org/10.3390/molecules27144548

Ejemplares similares

Thiocarbohydrazone and Chalcone-Derived 3,4-Dihydropyrimidinethione as Lipid Peroxidation and Soybean Lipoxygenase Inhibitors
por: Georgiou, Nikitas, et al.
Publicado: (2023)

Conformational Properties of New Thiosemicarbazone and Thiocarbohydrazone Derivatives and Their Possible Targets
por: Georgiou, Nikitas, et al.
Publicado: (2022)

A Journey to the Conformational Analysis of T-Cell Epitope Peptides Involved in Multiple Sclerosis
por: Koukoulitsa, Catherine, et al.
Publicado: (2020)

Rational Design and Synthesis of AT1R Antagonists
por: Georgiou, Nikitas, et al.
Publicado: (2021)

Exploration of Thiourea-Based Scaffolds for the Construction of Bacterial Ureases Inhibitors
por: Tabor, Wojciech, et al.
Publicado: (2023)

On the Rational Drug Design for Hypertension through NMR Spectroscopy
por: Chontzopoulou, Eleni, et al.
Publicado: (2020)

Unveiling the interaction profile of rosmarinic acid and its bioactive substructures with serum albumin
por: Papaemmanouil, Christina, et al.
Publicado: (2020)

Comparative Interaction Studies of Quercetin with 2-Hydroxyl-propyl-β-cyclodextrin and 2,6-Methylated-β-cyclodextrin
por: Vakali, Vasiliki, et al.
Publicado: (2022)

Losartan Interactions with 2-Hydroxypropyl-β-CD
por: Palli, Vasiliki, et al.
Publicado: (2022)

Synthesis and Bioactivity of Thiosemicarbazones Containing Adamantane Skeletons
por: Pham, Van Hien, et al.
Publicado: (2020)

An Overview on Target-Based Drug Design against Kinetoplastid Protozoan Infections: Human African Trypanosomiasis, Chagas Disease and Leishmaniases
por: Kourbeli, Violeta, et al.
Publicado: (2021)

Ethnopharmacological study of medicinal plants used against skin ailments on Mount Pelion, central Greece
por: Tsioutsiou, Efthymia Eleni, et al.
Publicado: (2023)

Exploring the Binding Effects of Natural Products and Antihypertensive Drugs on SARS-CoV-2: An In Silico Investigation of Main Protease and Spike Protein
por: Moschovou, Kalliopi, et al.
Publicado: (2023)

Assessment of Antioxidant and Antimicrobial Properties of Selected Greek Propolis Samples (North East Aegean Region Islands)
por: Pyrgioti, Elisavet, et al.
Publicado: (2022)

Conformational Analysis of Geometric Isomers of Pitavastatin Together with Their Lactonized Analogues
por: Makuc, Damjan, et al.
Publicado: (2013)

Investigation of the Biological Properties of (Hetero)Aromatic Thiosemicarbazones
por: Serda, Maciej, et al.
Publicado: (2012)

Computational and NMR spectroscopy insights into the conformation of cyclic di-nucleotides
por: Wang, Baifan, et al.
Publicado: (2017)

Metallocene-Naphthalimide Derivatives: The Effect of Geometry, DFT Methodology, and Transition Metals on Absorption Spectra
por: Tzeliou, Christina Eleftheria, et al.
Publicado: (2023)

NMR studies of anion-induced conformational changes in diindolylureas and diindolylthioureas
por: Makuc, Damjan, et al.
Publicado: (2011)

Phytochemical Study on Seeds of Paeonia clusii subsp. rhodia—Antioxidant and Anti-Tyrosinase Properties
por: Klontza, Vithleem, et al.
Publicado: (2023)

Benzaldehyde thiosemicarbazone
por: Kong, Lingqian, et al.
Publicado: (2008)

Antioxidant Properties of Camphene-Based Thiosemicarbazones: Experimental and Theoretical Evaluation
por: Yang, Lijuan, et al.
Publicado: (2020)

Review on the QM/MM Methodologies and Their Application to Metalloproteins
por: Tzeliou, Christina Eleftheria, et al.
Publicado: (2022)

Benzaldehyde thiosemicarbazone monohydrate
por: Gu, Sheng-Jiu, et al.
Publicado: (2008)

Medicinal Plants Used Traditionally for Skin Related Problems in the South Balkan and East Mediterranean Region—A Review
por: Tsioutsiou, Efthymia Eleni, et al.
Publicado: (2022)

Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper(II) Complex
por: Choo, Xin Yi, et al.
Publicado: (2022)

(E)-4-Octyloxybenzaldehyde thiosemicarbazone
por: Islam, M. A. A. A. A., et al.
Publicado: (2009)

3-Nitrobenzaldehyde thiosemicarbazone
por: Wu, De-Hong, et al.
Publicado: (2008)

Synthesis and Structural Characterization of Fluorinated Thiosemicarbazones
por: Bautista, Juan L., et al.
Publicado: (2013)

Modification of Polyacrylonitrile Fibers by Coupling to Thiosemicarbazones
por: Yao, Yao, et al.
Publicado: (2019)

Inhibition of Topoisomerases by Metal Thiosemicarbazone Complexes
por: Jiang, Xiaohua, et al.
Publicado: (2023)

Bioactive conformation I
por: Peters, Thomas
Publicado: (2007)

Putative Bioactive Motif of Tritrpticin Revealed by an Antibody with Biological Receptor-Like Properties
por: Sharma, Raghava, et al.
Publicado: (2013)

Photoswitchable Molecular Units with Tunable Nonlinear Optical Activity: A Theoretical Investigation
por: Avramopoulos, Aggelos, et al.
Publicado: (2023)

2,5-Dimethoxybenzaldehyde thiosemicarbazone
por: Fun, Hoong-Kun, et al.
Publicado: (2008)

Antifungal and Antioxidant Activities of Pyrrolidone Thiosemicarbazone Complexes
por: Al-Amiery, Ahmed A., et al.
Publicado: (2012)

Ferrocene-1-carbaldehyde thiosemicarbazone
por: Vikneswaran, M. R., et al.
Publicado: (2010)

4-Cyanobenzaldehyde thiosemicarbazone
por: Wu, De-Hong, et al.
Publicado: (2008)

3-Methoxybenzaldehyde thiosemicarbazone
por: Zhang, Jian, et al.
Publicado: (2009)

Pyridine-2-carbaldehyde thiosemicarbazone
por: Song, Li-Hua, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_bhh6kk8jcbuqg4en2s7jbrdmkl