Cytochrome P450 27C1 Level Dictates Lung Cancer Tumorigenicity and Sensitivity towards Multiple Anticancer Agents and Its Potential Interplay with the IGF-1R/Akt/p53 Signaling Pathway

Cytochrome P450 enzymes (CYP450s) exert mighty catalytic actions in cellular metabolism and detoxication, which play pivotal roles in cell fate determination. Preliminary data shows differential expression levels of CYP27C1, one of the “orphan P450s” in human lung cancer cell lines. Here, we study t...

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Detalles Bibliográficos
Autores principales: Mo, Hai-Ying, Wei, Qi-Yao, Zhong, Qiu-Hua, Zhao, Xiao-Yun, Guo, Dan, Han, Jin, Noracharttiyapot, Wachiraporn, Visser, Lydia, van den Berg, Anke, Xu, Yan-Ming, Lau, Andy T. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324654/
https://www.ncbi.nlm.nih.gov/pubmed/35887201
http://dx.doi.org/10.3390/ijms23147853

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