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The Increase in the Drug Resistance of Acute Myeloid Leukemia THP-1 Cells in High-Density Cell Culture Is Associated with Inflammatory-like Activation and Anti-Apoptotic Bcl-2 Proteins

It is known that cell culture density can modulate the drug resistance of acute myeloid leukemia (AML) cells. In this work, we studied the drug sensitivity of AML cells in high-density cell cultures (cell lines THP-1, HL-60, MV4-11, and U937). It was shown that the AML cells in high-density cell cul...

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Detalles Bibliográficos
Autores principales:	Kobyakova, Margarita, Lomovskaya, Yana, Senotov, Anatoly, Lomovsky, Alexey, Minaychev, Vladislav, Fadeeva, Irina, Shtatnova, Daria, Krasnov, Kirill, Zvyagina, Alena, Odinokova, Irina, Akatov, Vladimir, Fadeev, Roman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324792/ https://www.ncbi.nlm.nih.gov/pubmed/35887226 http://dx.doi.org/10.3390/ijms23147881

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