Blood biomarkers for HIV infection with focus on neurologic complications—A review

Although clinical examinations, neuroimaging, and cerebrospinal fluid analyses are the most important ways to evaluate the impact of HIV infection on the brain and in diagnosis of opportunistic infections, several blood biomarkers including HIV RNA concentrations, CD4 +T‐cell count, and neurofilamen...

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Detalles Bibliográficos
Autores principales: Hagberg, Lars, Edén, Arvid, Zetterberg, Henrik, Price, Richard W., Gisslén, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324809/
https://www.ncbi.nlm.nih.gov/pubmed/35470863
http://dx.doi.org/10.1111/ane.13629
Descripción
Sumario:Although clinical examinations, neuroimaging, and cerebrospinal fluid analyses are the most important ways to evaluate the impact of HIV infection on the brain and in diagnosis of opportunistic infections, several blood biomarkers including HIV RNA concentrations, CD4 +T‐cell count, and neurofilament light chain protein (NfL) concentration, along with tests for opportunistic infections can provide important information for clinical decisions.

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