Cargando…

A New EGFR Inhibitor from Ficus benghalensis Exerted Potential Anti-Inflammatory Activity via Akt/PI3K Pathway Inhibition

Inflammation is a critical defensive mechanism mainly arising due to the production of prostaglandins via cyclooxygenase enzymes. This study aimed to examine the anti-inflammatory activity of fatty acid glucoside (FAG), which is isolated from Ficus benghalensis against lipopolysaccharide (LPS)-stimu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alaaeldin, Rania, Hassan, Heba Ali, Abdel-Rahman, Islam M., Mohyeldin, Reham H., Youssef, Nancy, Allam, Ahmed E., Abdelwahab, Sayed F., Zhao, Qing-Li, Fathy, Moustafa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324879/ https://www.ncbi.nlm.nih.gov/pubmed/35877429 http://dx.doi.org/10.3390/cimb44070205

Ejemplares similares

Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway
por: Alaaeldin, Rania, et al.
Publicado: (2021)

Isolation and characterization of novel acetylcholinesterase inhibitors from Ficus benghalensis L. leaves
por: Hassan, Heba Ali, et al.
Publicado: (2020)

Phytochemistry, Pharmacological Properties, and Recent Applications of Ficus benghalensis and Ficus religiosa
por: Murugesu, Suganya, et al.
Publicado: (2021)

Wound-healing activity of ethanolic and aqueous extracts of Ficus benghalensis
por: Garg, Vipin Kumar, et al.
Publicado: (2011)

Effect of root-extracts of Ficus benghalensis (Banyan) in pain in animal models
por: Panday, Dipesh Raj, et al.
Publicado: (2016)

Enzyme Inhibitory Activities of Extracts and Carpachromene from the Stem of Ficus benghalensis
por: Rauf, Abdur, et al.
Publicado: (2022)

Genome sequencing and comparative analysis of Ficus benghalensis and Ficus religiosa species reveal evolutionary mechanisms of longevity
por: Chakraborty, Abhisek, et al.
Publicado: (2022)

Vincamine Ameliorates Epithelial-Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis in Rats; Targeting TGF-β/MAPK/Snai1 Pathway
por: Alaaeldin, Rania, et al.
Publicado: (2023)

Antioxidant and Immunomodulatory Activity of Hydroalcoholic Extract and its Fractions of Leaves of Ficus benghalensis Linn.
por: Bhanwase, Anil Subhash, et al.
Publicado: (2016)

In vitro and in silico anti-oxidant, cytotoxicity and biological activities of Ficus benghalensis and Duranta repens
por: Khanal, Pukar, et al.
Publicado: (2020)

In-vitro antioxidant potential and acetylcholinesterase inhibitory effect of Ficus benghalensis aerial root extract
por: Ramasamy, Anand, et al.
Publicado: (2022)

Azilsartan Modulates HMGB1/NF-κB/p38/ERK1/2/JNK and Apoptosis Pathways during Renal Ischemia Reperfusion Injury
por: Alaaeldin, Rania, et al.
Publicado: (2023)

Amelioration of Scopolamine-Induced Amnesic, Anxiolytic and Antidepressant Effects of Ficus benghalensis in Behavioral Experimental Models
por: Malik, Humna, et al.
Publicado: (2020)

Effect of Pelargonidin isolated from Ficus benghalensis L. on phenotypic changes in zebrafish (Danio rerio) embryos
por: Kundap, Uday, et al.
Publicado: (2017)

Removal of Brilliant Green Dye from Water Using Ficus benghalensis Tree Leaves as an Efficient Biosorbent
por: Gul, Salma, et al.
Publicado: (2023)

Effect of root-extracts of Ficus benghalensis (Banyan) in memory, anxiety, muscle co-ordination and seizure in animal models
por: Panday, Dipesh Raj, et al.
Publicado: (2016)

Ficus benghalensis as Potential Inhibitor of 5α-Reductase for Hair Growth Promotion: In Vitro, In Silico, and In Vivo Evaluation
por: Iltaf, Jawaria, et al.
Publicado: (2021)

Micromorphology, Ultrastructure and Histochemistry of Commelina benghalensis L. Leaves and Stems
por: Doolabh, Kareshma, et al.
Publicado: (2021)

Identification of surfactins and iturins produced by potent fungal antagonist, Bacillus subtilis K1 isolated from aerial roots of banyan (Ficus benghalensis) tree using mass spectrometry
por: Pathak, Khyati V., et al.
Publicado: (2013)

Application of extracellular lipopeptide biosurfactant produced by endophytic Bacillus subtilis K1 isolated from aerial roots of banyan (Ficus benghalensis) in microbially enhanced oil recovery (MEOR)
por: Pathak, Khyati V., et al.
Publicado: (2013)

Fangchinoline exerts antitumour activity by suppressing the EGFR-PI3K/AKT signalling pathway in colon adenocarcinoma
por: Jiang, Fengqi, et al.
Publicado: (2021)

Effect of surface treatments on biaxial flexural strength, fatigue resistance, and fracture toughness of high versus low translucency zirconia
por: Elraggal, Alaaeldin, et al.
Publicado: (2022)

Syringin exerts anti-breast cancer effects through PI3K-AKT and EGFR-RAS-RAF pathways
por: Wang, Fei, et al.
Publicado: (2022)

Identification of genes associated with ricinoleic acid accumulation in Hiptage benghalensis via transcriptome analysis
por: Tian, Bo, et al.
Publicado: (2019)

Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation
por: Alaaeldin, Rania, et al.
Publicado: (2022)

Inhibition of NF-kB/IL-6/JAK2/STAT3 Pathway and Epithelial-Mesenchymal Transition in Breast Cancer Cells by Azilsartan
por: Alaaeldin, Rania, et al.
Publicado: (2022)

MicroRNA-1231 exerts a tumor suppressor role through regulating the EGFR/PI3K/AKT axis in glioma
por: Zhang, Jiale, et al.
Publicado: (2018)

Semi-purified extracts of Commelina benghalensis (Commelinaceae) induce apoptosis and cell cycle arrest in Jurkat-T cells
por: Lebogo, Kgomotso Welheminah, et al.
Publicado: (2014)

Antipyretic, Antinociceptive, and Anti-Inflammatory Activities from Pogostemon benghalensis Leaf Extract in Experimental Wister Rats
por: Aryal, Sushant, et al.
Publicado: (2019)

Capsaicin and sorafenib combination treatment exerts synergistic anti-hepatocellular carcinoma activity by suppressing EGFR and PI3K/Akt/mTOR signaling
por: Dai, Ninggao, et al.
Publicado: (2018)

Jatrophone: a cytotoxic macrocylic diterpene targeting PI3K/AKT/NF-κB pathway, inducing apoptosis and autophagy in resistant breast cancer cells
por: Shari, Khawlah, et al.
Publicado: (2023)

Terpenoid natural products exert neuroprotection via the PI3K/Akt pathway
por: Xu, Bingyao, et al.
Publicado: (2022)

Ficus umbellata Vahl. (Moraceae) Stem Bark Extracts Exert Antitumor Activities In Vitro and In Vivo
por: Silihe, Kevine Kamga, et al.
Publicado: (2017)

Targeting EGFR/PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma
por: Bang, Jieun, et al.
Publicado: (2023)

Effect of erosive media on microhardness and fracture toughness of CAD-CAM dental materials
por: Elraggal, Alaaeldin, et al.
Publicado: (2022)

Phosphorylated Akt Protein at Ser473 Enables HeLa Cells to Tolerate Nutrient-Deprived Conditions
por: Fathy, Moustafa, et al.
Publicado: (2017)

Blackberry-Loaded AgNPs Attenuate Hepatic Ischemia/Reperfusion Injury via PI3K/Akt/mTOR Pathway
por: Fathi, Ahmed M., et al.
Publicado: (2023)

Eugenol Exerts Apoptotic Effect and Modulates the Sensitivity of HeLa Cells to Cisplatin and Radiation
por: Fathy, Moustafa, et al.
Publicado: (2019)

Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance
por: Chang, Kwang-Yu, et al.
Publicado: (2013)

JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation
por: Zhang, Bo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_25dmd46779pd5c5676mo5126sq