Targeted Next-Generation Sequencing of Thymic Epithelial Tumours Revealed Pathogenic Variants in KIT, ERBB2, KRAS, and TP53 in 30% of Thymic Carcinomas

SIMPLE SUMMARY: The biology of thymic epithelial tumours (TETs), including thymomas and thymic carcinomas, and particularly the extent of molecular dysregulation, is poorly understood. Through next-generation sequencing of 15 genes implicated in common solid tumours in 53 TETs, we found a larger num...

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Autores principales: Szpechcinski, Adam, Szolkowska, Malgorzata, Winiarski, Sebastian, Lechowicz, Urszula, Wisniewski, Piotr, Knetki-Wroblewska, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324890/
https://www.ncbi.nlm.nih.gov/pubmed/35884448
http://dx.doi.org/10.3390/cancers14143388

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