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Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease Dementia (ADD): Using the “Doors and People” Tool to Differentiate between Early aMCI—Late aMCI—Mild ADD Diagnostic Groups

Episodic memory is the type of memory that allows the recollection of personal experiences containing information on what has happened and, also, where and when it happened. Because of its sensitivity to neurodegenerative diseases and the aging of the brain, it is considered a hallmark of Alzheimer’...

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Autores principales: Chatzikostopoulos, Athanasios, Moraitou, Despina, Tsolaki, Magdalini, Masoura, Elvira, Papantoniou, Georgia, Sofologi, Maria, Papaliagkas, Vasileios, Kougioumtzis, Georgios, Papatzikis, Efthymios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324962/
https://www.ncbi.nlm.nih.gov/pubmed/35885671
http://dx.doi.org/10.3390/diagnostics12071768
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author Chatzikostopoulos, Athanasios
Moraitou, Despina
Tsolaki, Magdalini
Masoura, Elvira
Papantoniou, Georgia
Sofologi, Maria
Papaliagkas, Vasileios
Kougioumtzis, Georgios
Papatzikis, Efthymios
author_facet Chatzikostopoulos, Athanasios
Moraitou, Despina
Tsolaki, Magdalini
Masoura, Elvira
Papantoniou, Georgia
Sofologi, Maria
Papaliagkas, Vasileios
Kougioumtzis, Georgios
Papatzikis, Efthymios
author_sort Chatzikostopoulos, Athanasios
collection PubMed
description Episodic memory is the type of memory that allows the recollection of personal experiences containing information on what has happened and, also, where and when it happened. Because of its sensitivity to neurodegenerative diseases and the aging of the brain, it is considered a hallmark of Alzheimer’s disease dementia (ADD). The objective of the present study was to examine episodic memory in amnestic mild cognitive impairment (aMCI) and ADD. Patients with the diagnosis of early aMCI, late aMCI, and mild ADD were evaluated using the Doors and People tool which consists of four subtests examining different aspects of episodic memory. The statistical analysis with receiver operating characteristic curves (ROC) showed the discriminant potential and the cutoffs of every subtest. Overall, the evaluation of episodic memory with the Doors and People tool can discriminate with great sensitivity between the different groups of people with AD and, especially, early aMCI, late aMCI, and mild ADD patients.
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spelling pubmed-93249622022-07-27 Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease Dementia (ADD): Using the “Doors and People” Tool to Differentiate between Early aMCI—Late aMCI—Mild ADD Diagnostic Groups Chatzikostopoulos, Athanasios Moraitou, Despina Tsolaki, Magdalini Masoura, Elvira Papantoniou, Georgia Sofologi, Maria Papaliagkas, Vasileios Kougioumtzis, Georgios Papatzikis, Efthymios Diagnostics (Basel) Article Episodic memory is the type of memory that allows the recollection of personal experiences containing information on what has happened and, also, where and when it happened. Because of its sensitivity to neurodegenerative diseases and the aging of the brain, it is considered a hallmark of Alzheimer’s disease dementia (ADD). The objective of the present study was to examine episodic memory in amnestic mild cognitive impairment (aMCI) and ADD. Patients with the diagnosis of early aMCI, late aMCI, and mild ADD were evaluated using the Doors and People tool which consists of four subtests examining different aspects of episodic memory. The statistical analysis with receiver operating characteristic curves (ROC) showed the discriminant potential and the cutoffs of every subtest. Overall, the evaluation of episodic memory with the Doors and People tool can discriminate with great sensitivity between the different groups of people with AD and, especially, early aMCI, late aMCI, and mild ADD patients. MDPI 2022-07-21 /pmc/articles/PMC9324962/ /pubmed/35885671 http://dx.doi.org/10.3390/diagnostics12071768 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chatzikostopoulos, Athanasios
Moraitou, Despina
Tsolaki, Magdalini
Masoura, Elvira
Papantoniou, Georgia
Sofologi, Maria
Papaliagkas, Vasileios
Kougioumtzis, Georgios
Papatzikis, Efthymios
Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease Dementia (ADD): Using the “Doors and People” Tool to Differentiate between Early aMCI—Late aMCI—Mild ADD Diagnostic Groups
title Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease Dementia (ADD): Using the “Doors and People” Tool to Differentiate between Early aMCI—Late aMCI—Mild ADD Diagnostic Groups
title_full Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease Dementia (ADD): Using the “Doors and People” Tool to Differentiate between Early aMCI—Late aMCI—Mild ADD Diagnostic Groups
title_fullStr Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease Dementia (ADD): Using the “Doors and People” Tool to Differentiate between Early aMCI—Late aMCI—Mild ADD Diagnostic Groups
title_full_unstemmed Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease Dementia (ADD): Using the “Doors and People” Tool to Differentiate between Early aMCI—Late aMCI—Mild ADD Diagnostic Groups
title_short Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease Dementia (ADD): Using the “Doors and People” Tool to Differentiate between Early aMCI—Late aMCI—Mild ADD Diagnostic Groups
title_sort episodic memory in amnestic mild cognitive impairment (amci) and alzheimer’s disease dementia (add): using the “doors and people” tool to differentiate between early amci—late amci—mild add diagnostic groups
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324962/
https://www.ncbi.nlm.nih.gov/pubmed/35885671
http://dx.doi.org/10.3390/diagnostics12071768
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