Efficient Editing of the ZBED6-Binding Site in Intron 3 of IGF2 in a Bovine Model Using the CRISPR/Cas9 System

Background: Insulin-like growth factor 2 is a growth-promoting factor that plays an important role in the growth and development of mammals. A nucleotide substitution in intron 3 of IGF2—which disrupts the ZBED6-binding site—affects muscle mass, organ size, and fat deposition in pigs. The ZBED6-bind...

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Detalles Bibliográficos
Autores principales: Zou, Huiying, Yu, Dawei, Yao, Shun, Ding, Fangrong, Li, Junliang, Li, Ling, Li, Xue, Zhao, Shanjiang, Pang, Yunwei, Hao, Haisheng, Du, Weihua, Zhao, Xueming, Dai, Yunping, Zhu, Huabin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325003/
https://www.ncbi.nlm.nih.gov/pubmed/35885915
http://dx.doi.org/10.3390/genes13071132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325003/
https://www.ncbi.nlm.nih.gov/pubmed/35885915
http://dx.doi.org/10.3390/genes13071132

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