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Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review
Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women’s physical and mental...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325244/ https://www.ncbi.nlm.nih.gov/pubmed/35889348 http://dx.doi.org/10.3390/molecules27144476 |
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author | Chen, Tong Jia, Fan Yu, Yue Zhang, Wufan Wang, Chaoying Zhu, Shiqin Zhang, Nana Liu, Xinmin |
author_facet | Chen, Tong Jia, Fan Yu, Yue Zhang, Wufan Wang, Chaoying Zhu, Shiqin Zhang, Nana Liu, Xinmin |
author_sort | Chen, Tong |
collection | PubMed |
description | Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women’s physical and mental health. Quercetin (QUR) is a natural compound of flavonoids found in a variety of foods and medicinal plants. It can intervene with the pathologic process of PCOS from multiple targets and channels and has few adverse reactions. It is mentioned in this review that QUR can improve ovulation disorder, relieve Insulin resistance (IR), reduce androgen, regulate lipid metabolism, regulate gut microbiota and improve vascular endothelial function, which is of great significance in the treatment of PCOS. |
format | Online Article Text |
id | pubmed-9325244 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93252442022-07-27 Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review Chen, Tong Jia, Fan Yu, Yue Zhang, Wufan Wang, Chaoying Zhu, Shiqin Zhang, Nana Liu, Xinmin Molecules Review Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women’s physical and mental health. Quercetin (QUR) is a natural compound of flavonoids found in a variety of foods and medicinal plants. It can intervene with the pathologic process of PCOS from multiple targets and channels and has few adverse reactions. It is mentioned in this review that QUR can improve ovulation disorder, relieve Insulin resistance (IR), reduce androgen, regulate lipid metabolism, regulate gut microbiota and improve vascular endothelial function, which is of great significance in the treatment of PCOS. MDPI 2022-07-13 /pmc/articles/PMC9325244/ /pubmed/35889348 http://dx.doi.org/10.3390/molecules27144476 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chen, Tong Jia, Fan Yu, Yue Zhang, Wufan Wang, Chaoying Zhu, Shiqin Zhang, Nana Liu, Xinmin Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
title | Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
title_full | Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
title_fullStr | Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
title_full_unstemmed | Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
title_short | Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review |
title_sort | potential role of quercetin in polycystic ovary syndrome and its complications: a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325244/ https://www.ncbi.nlm.nih.gov/pubmed/35889348 http://dx.doi.org/10.3390/molecules27144476 |
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