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Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review

Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women’s physical and mental...

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Detalles Bibliográficos
Autores principales: Chen, Tong, Jia, Fan, Yu, Yue, Zhang, Wufan, Wang, Chaoying, Zhu, Shiqin, Zhang, Nana, Liu, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325244/
https://www.ncbi.nlm.nih.gov/pubmed/35889348
http://dx.doi.org/10.3390/molecules27144476
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author Chen, Tong
Jia, Fan
Yu, Yue
Zhang, Wufan
Wang, Chaoying
Zhu, Shiqin
Zhang, Nana
Liu, Xinmin
author_facet Chen, Tong
Jia, Fan
Yu, Yue
Zhang, Wufan
Wang, Chaoying
Zhu, Shiqin
Zhang, Nana
Liu, Xinmin
author_sort Chen, Tong
collection PubMed
description Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women’s physical and mental health. Quercetin (QUR) is a natural compound of flavonoids found in a variety of foods and medicinal plants. It can intervene with the pathologic process of PCOS from multiple targets and channels and has few adverse reactions. It is mentioned in this review that QUR can improve ovulation disorder, relieve Insulin resistance (IR), reduce androgen, regulate lipid metabolism, regulate gut microbiota and improve vascular endothelial function, which is of great significance in the treatment of PCOS.
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spelling pubmed-93252442022-07-27 Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review Chen, Tong Jia, Fan Yu, Yue Zhang, Wufan Wang, Chaoying Zhu, Shiqin Zhang, Nana Liu, Xinmin Molecules Review Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women’s physical and mental health. Quercetin (QUR) is a natural compound of flavonoids found in a variety of foods and medicinal plants. It can intervene with the pathologic process of PCOS from multiple targets and channels and has few adverse reactions. It is mentioned in this review that QUR can improve ovulation disorder, relieve Insulin resistance (IR), reduce androgen, regulate lipid metabolism, regulate gut microbiota and improve vascular endothelial function, which is of great significance in the treatment of PCOS. MDPI 2022-07-13 /pmc/articles/PMC9325244/ /pubmed/35889348 http://dx.doi.org/10.3390/molecules27144476 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chen, Tong
Jia, Fan
Yu, Yue
Zhang, Wufan
Wang, Chaoying
Zhu, Shiqin
Zhang, Nana
Liu, Xinmin
Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review
title Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review
title_full Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review
title_fullStr Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review
title_full_unstemmed Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review
title_short Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review
title_sort potential role of quercetin in polycystic ovary syndrome and its complications: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325244/
https://www.ncbi.nlm.nih.gov/pubmed/35889348
http://dx.doi.org/10.3390/molecules27144476
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