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Development of New Potential Inhibitors of β1 Integrins through In Silico Methods—Screening and Computational Validation

Integrins are transmembrane receptors that play a critical role in many biological processes which can be therapeutically modulated using integrin blockers, such as peptidomimetic ligands. This work aimed to develop new potential β1 integrin antagonists using modeled receptors based on the aligned c...

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Detalles Bibliográficos
Autores principales:	Vasconcelos, Disraeli, Chaves, Beatriz, Albuquerque, Aline, Andrade, Luca, Henriques, Andrielly, Sartori, Geraldo, Savino, Wilson, Caffarena, Ernesto, Martins-Da-Silva, João Herminio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325263/ https://www.ncbi.nlm.nih.gov/pubmed/35888022 http://dx.doi.org/10.3390/life12070932

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