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Comparison of Rapid Cognitive Screen against Montreal Cognitive Assessment in screening for cognitive impairment in the old and old‐old

BACKGROUND: The Montreal Cognitive Assessment (MoCA) was developed as a screening tool for mild cognitive impairment (MCI). Given the need for a rapid screening test in settings such as primary care, we compare the validity of the Rapid Cognitive Screen (RCS) against the MoCA, and determine cut‐off...

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Autores principales: Chen, Matthew Zhixuan, Chan, Yiong Huak, Wong, Michael Wai Kit, Merchant, Reshma Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325369/
https://www.ncbi.nlm.nih.gov/pubmed/35577347
http://dx.doi.org/10.1111/psyg.12841
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author Chen, Matthew Zhixuan
Chan, Yiong Huak
Wong, Michael Wai Kit
Merchant, Reshma Aziz
author_facet Chen, Matthew Zhixuan
Chan, Yiong Huak
Wong, Michael Wai Kit
Merchant, Reshma Aziz
author_sort Chen, Matthew Zhixuan
collection PubMed
description BACKGROUND: The Montreal Cognitive Assessment (MoCA) was developed as a screening tool for mild cognitive impairment (MCI). Given the need for a rapid screening test in settings such as primary care, we compare the validity of the Rapid Cognitive Screen (RCS) against the MoCA, and determine cut‐off scores in the old and old‐old. METHODS: Cross‐sectional study involving community‐dwelling ‘old’ (65 to 79 years old) and ‘old‐old’ (≥ 80 years old) without dementia. Cognitive impairment was defined by MoCA score 17 to 22. Validation was done using the receiver operating characteristic (ROC) curve analysis: area under the curve (AUC), sensitivity (Sn), and specificity (Sp). RESULTS: Of the 183 participants (mean age 72.1 ± 5.2 years),15.8% (n = 29) were classified as cognitively impaired. The overall ROC curve had an AUC of 0.82 (95% CI 0.75–0.90, P < 0.01) with an optimal cut‐off of 7/8 on RCS (Sn 0.77, Sp 0.72). The ‘old’ and ‘old‐old’ group had AUC of 0.82 (95% CI 0.74–0.91, P < 0.01) with 8/9 as optimal cut‐off (Sn 0.51, Sp 0.96) and AUC of 0.85 (95% CI 0.66–1.03, P < 0.01) with 7/8 as optimal cut‐off (Sn 0.71, Sp 1.00) respectively. In multivariate analysis, age was associated with 0.05 (95% CI ‐0.10‐0.00, P < 0.04) point decrement, while >6 years of education was associated with 0.82 (95% CI 0.32–1.33, P < 0.01) point increment in RCS scores. CONCLUSION: The three‐item RCS is quick and easy to administer. Although RCS met the criterion for good validity against MoCA in predicting cognitive impairment, its utility as a first‐line screening tool needs to be further validated in a large‐scale population study.
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spelling pubmed-93253692022-07-30 Comparison of Rapid Cognitive Screen against Montreal Cognitive Assessment in screening for cognitive impairment in the old and old‐old Chen, Matthew Zhixuan Chan, Yiong Huak Wong, Michael Wai Kit Merchant, Reshma Aziz Psychogeriatrics Original Articles BACKGROUND: The Montreal Cognitive Assessment (MoCA) was developed as a screening tool for mild cognitive impairment (MCI). Given the need for a rapid screening test in settings such as primary care, we compare the validity of the Rapid Cognitive Screen (RCS) against the MoCA, and determine cut‐off scores in the old and old‐old. METHODS: Cross‐sectional study involving community‐dwelling ‘old’ (65 to 79 years old) and ‘old‐old’ (≥ 80 years old) without dementia. Cognitive impairment was defined by MoCA score 17 to 22. Validation was done using the receiver operating characteristic (ROC) curve analysis: area under the curve (AUC), sensitivity (Sn), and specificity (Sp). RESULTS: Of the 183 participants (mean age 72.1 ± 5.2 years),15.8% (n = 29) were classified as cognitively impaired. The overall ROC curve had an AUC of 0.82 (95% CI 0.75–0.90, P < 0.01) with an optimal cut‐off of 7/8 on RCS (Sn 0.77, Sp 0.72). The ‘old’ and ‘old‐old’ group had AUC of 0.82 (95% CI 0.74–0.91, P < 0.01) with 8/9 as optimal cut‐off (Sn 0.51, Sp 0.96) and AUC of 0.85 (95% CI 0.66–1.03, P < 0.01) with 7/8 as optimal cut‐off (Sn 0.71, Sp 1.00) respectively. In multivariate analysis, age was associated with 0.05 (95% CI ‐0.10‐0.00, P < 0.04) point decrement, while >6 years of education was associated with 0.82 (95% CI 0.32–1.33, P < 0.01) point increment in RCS scores. CONCLUSION: The three‐item RCS is quick and easy to administer. Although RCS met the criterion for good validity against MoCA in predicting cognitive impairment, its utility as a first‐line screening tool needs to be further validated in a large‐scale population study. John Wiley & Sons Australia, Ltd 2022-05-16 2022-07 /pmc/articles/PMC9325369/ /pubmed/35577347 http://dx.doi.org/10.1111/psyg.12841 Text en © 2022 The Authors. Psychogeriatrics published by John Wiley & Sons Australia, Ltd on behalf of Japanese Psychogeriatric Society. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Chen, Matthew Zhixuan
Chan, Yiong Huak
Wong, Michael Wai Kit
Merchant, Reshma Aziz
Comparison of Rapid Cognitive Screen against Montreal Cognitive Assessment in screening for cognitive impairment in the old and old‐old
title Comparison of Rapid Cognitive Screen against Montreal Cognitive Assessment in screening for cognitive impairment in the old and old‐old
title_full Comparison of Rapid Cognitive Screen against Montreal Cognitive Assessment in screening for cognitive impairment in the old and old‐old
title_fullStr Comparison of Rapid Cognitive Screen against Montreal Cognitive Assessment in screening for cognitive impairment in the old and old‐old
title_full_unstemmed Comparison of Rapid Cognitive Screen against Montreal Cognitive Assessment in screening for cognitive impairment in the old and old‐old
title_short Comparison of Rapid Cognitive Screen against Montreal Cognitive Assessment in screening for cognitive impairment in the old and old‐old
title_sort comparison of rapid cognitive screen against montreal cognitive assessment in screening for cognitive impairment in the old and old‐old
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325369/
https://www.ncbi.nlm.nih.gov/pubmed/35577347
http://dx.doi.org/10.1111/psyg.12841
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