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Conjugated detergent micelles as a platform for IgM purification

Immunoglobulin M (IgM) antibodies hold promise as anticancer drugs and as agents for promoting immune homeostasis. This promise has not been realized due to low expression levels in mammalian cells producing IgM class antibodies, and the failure of protein A chromatography for IgM purification. Here...

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Detalles Bibliográficos
Autores principales: Dhandapani, Gunasekaran, Wachtel, Ellen, Das, Ishita, Sheves, Mordechai, Patchornik, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325453/
https://www.ncbi.nlm.nih.gov/pubmed/35324016
http://dx.doi.org/10.1002/bit.28089

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