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Conjugated detergent micelles as a platform for IgM purification
Immunoglobulin M (IgM) antibodies hold promise as anticancer drugs and as agents for promoting immune homeostasis. This promise has not been realized due to low expression levels in mammalian cells producing IgM class antibodies, and the failure of protein A chromatography for IgM purification. Here...
Autores principales: | Dhandapani, Gunasekaran, Wachtel, Ellen, Das, Ishita, Sheves, Mordechai, Patchornik, Guy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325453/ https://www.ncbi.nlm.nih.gov/pubmed/35324016 http://dx.doi.org/10.1002/bit.28089 |
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