Cargando…

Progression of Type 1 Diabetes: Circulating MicroRNA Expression Profiles Changes from Preclinical to Overt Disease

OBJECTIVES: To evaluate the potential biological involvement of miRNA expression in the immune response and beta cell function in T1D. METHODS: We screened 377 serum miRNAs of 110 subjects divided into four groups: healthy individuals (control group) and patients at different stages of T1D progressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santos, Aritania Sousa, Ferreira, Ludmila Rodrigues Pinto, da Silva, Amanda Cabral, Alves, Laís Isidoro, Damasceno, Jullian Gabriel, Kulikowski, Leslie, Cunha-Neto, Edecio, da Silva, Maria Elizabeth Rossi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325579/ https://www.ncbi.nlm.nih.gov/pubmed/35903753 http://dx.doi.org/10.1155/2022/2734490

Ejemplares similares

Increased Expression of Circulating microRNA 101-3p in Type 1 Diabetes Patients: New Insights Into miRNA-Regulated Pathophysiological Pathways for Type 1 Diabetes
por: Santos, Aritania S., et al.
Publicado: (2019)

Prevalence of Inflammatory Pathways Over Immuno-Tolerance in Peripheral Blood Mononuclear Cells of Recent-Onset Type 1 Diabetes
por: Santos, Aritania Sousa, et al.
Publicado: (2022)

A Major Downregulation of Circulating microRNAs in Zika Acutely Infected Patients: Potential Implications in Innate and Adaptive Immune Response Signaling Pathways
por: Carvalho-Silva, Ana Carolina, et al.
Publicado: (2022)

Differential microRNA Profile in Operational Tolerance: A Potential Role in Favoring Cell Survival
por: Cabral, Amanda, et al.
Publicado: (2019)

Circulating Betatrophin Is Increased in Patients with Overt and Subclinical Hypothyroidism
por: Han, Cheng, et al.
Publicado: (2016)

MiRNA-30d and miR-770-5p as potential clinical risk predictors of Vasoplegic Syndrome in Patients undergoing on-pump coronary artery bypass grafting
por: Vilca Mejia, Omar Asdrúbal, et al.
Publicado: (2023)

Impact of the timing of capsule endoscopy in overt obscure gastrointestinal bleeding on yield and rebleeding rate - is sooner than 14 d advisable?
por: Gomes, Catarina, et al.
Publicado: (2018)

Plants used by the rural community of Bananal, Mato Grosso, Brazil: Aspects of popular knowledge
por: Miguéis, Graciela da Silva, et al.
Publicado: (2019)

Induction of IL-12 Production in Human Peripheral Monocytes by Trypanosoma cruzi Is Mediated by Glycosylphosphatidylinositol-Anchored Mucin-Like Glycoproteins and Potentiated by IFN-γ and CD40-CD40L Interactions
por: Abel, Lúcia Cristina Jamli, et al.
Publicado: (2014)

Influence of demographic and metabolic variables on forearm blood flow and vascular conductance in individuals without overt heart disease
por: Sartori, Thiago E, et al.
Publicado: (2010)

Mitochondria as a Cellular Hub in Infection and Inflammation
por: Andrieux, Pauline, et al.
Publicado: (2021)

Chagas Disease Cardiomyopathy: Immunopathology and Genetics
por: Cunha-Neto, Edecio, et al.
Publicado: (2014)

Diabetes related phenotypes and their influence on outcomes of patients with corona virus disease 2019 (COVID-19)
por: Alves, Lais Isidoro, et al.
Publicado: (2023)

Immunology and Infection by Protozoan Parasites
por: Cunha-Neto, Edecio, et al.
Publicado: (2015)

Effectiveness of Polyphenols on Perinatal Brain Damage: A Systematic Review of Preclinical Studies
por: Pontes, Paula Brielle, et al.
Publicado: (2023)

Association of interleukin 21 receptor gene variants with autoimune diseases in a type 1 diabetes cohort
por: Semzezem, Cintia, et al.
Publicado: (2015)

Editorial: Mitochondria at the Crossroads of Immunity and Inflammatory Tissue Damage
por: Nunes, João Paulo Silva, et al.
Publicado: (2021)

Circulating Omentin-1 Levels Are Decreased in Dilated Cardiomyopathy Patients with Overt Heart Failure
por: Huang, Ying, et al.
Publicado: (2016)

Overt Diabetes in Pregnancy
por: Goyal, Alpesh, et al.
Publicado: (2022)

CD226 rs763361 Is Associated with the Susceptibility to Type 1 Diabetes and Greater Frequency of GAD65 Autoantibody in a Brazilian Cohort
por: Mattana, Teresa Cristina Colvara, et al.
Publicado: (2014)

Genetic, laboratory and clinical risk factors in the development of overt ischemic stroke in children with sickle cell disease
por: Belisário, André Rolim, et al.
Publicado: (2018)

Importance of Zinc Transporter 8 Autoantibody in the Diagnosis of Type 1 Diabetes in Latin Americans
por: Gomes, Karla Fabiana Brasil, et al.
Publicado: (2017)

Between Deserts and Jungles: The Emergence and Circulation of Sylvatic Plague (1920-1950)
por: Alves Duarte da Silva, Matheus
Publicado: (2023)

Plasma Cytokine Profile in Tropical Endomyocardial Fibrosis: Predominance of TNF-a, IL-4 and IL-10
por: Bossa, Aline S., et al.
Publicado: (2014)

An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice
por: Magro, D.A.C., et al.
Publicado: (2013)

Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection
por: Ferreira, Ludmila Rodrigues Pinto, et al.
Publicado: (2017)

Hemostasis in Overt and Subclinical Hyperthyroidism
por: Ordookhani, Arash, et al.
Publicado: (2017)

Correction to: Overt Diabetes in Pregnancy
por: Goyal, Alpesh, et al.
Publicado: (2022)

Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?
por: Real, Juliana Monte, et al.
Publicado: (2018)

Circulating miR-1 as a potential biomarker of doxorubicin-induced cardiotoxicity in breast cancer patients
por: Oliveira-Carvalho Vagner, Rigaud, et al.
Publicado: (2016)

Local IgE in patients with allergic rhinitis
por: Rodrigues, Adriana Teixeira, et al.
Publicado: (2015)

Vector Competence of Culex quinquefasciatus from Brazil for West Nile Virus
por: Reis, Lúcia Aline Moura, et al.
Publicado: (2023)

MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice: Parasitological and Cardiological Outcomes
por: Navarro, Isabela Cunha, et al.
Publicado: (2015)

Overt hepatic encephalopathy in Italy: clinical outcomes and healthcare costs
por: Roggeri, Daniela Paola, et al.
Publicado: (2015)

Overt and non-overt disseminated intravascular coagulation and the potential role of heparin in the COVID-19 pandemic outbreak
por: Salamanna, Francesca, et al.
Publicado: (2020)

Flavonoids as Therapeutic Agents in Alzheimer's and Parkinson's Diseases: A Systematic Review of Preclinical Evidences
por: de Andrade Teles, Roxana Braga, et al.
Publicado: (2018)

Contribution to the Preclinical Safety Assessment of Lannea velutina and Sorindeia juglandifolia Leaves
por: Malú, Quintino, et al.
Publicado: (2022)

Evidence for T Cell Help in the IgG Response against Tandemly Repetitive Trypanosoma cruzi B13 Protein in Chronic Chagas Disease Patients
por: Duranti, Marcia, et al.
Publicado: (2012)

Preclinical Evaluation of Lipid-Based Nanosystems
por: Silva, Ana Catarina, et al.
Publicado: (2021)

In Vitro Validation of Antiparasitic Activity of PLA-Nanoparticles of Sodium Diethyldithiocarbamate against Trypanosoma cruzi
por: de Freitas Oliveira, Johny Wysllas, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bgt6j3j2kllt5kbvsn1gbegmn8