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Sialylated and sulfated N-Glycans in MDCK and engineered MDCK cells for influenza virus studies

The Madin-Darby canine kidney (MDCK) cell line is an in vitro model for influenza A virus (IAV) infection and propagation. MDCK-SIAT1 (SIAT1) and humanized MDCK (hCK) cell lines are engineered MDCK cells that express N-glycans with elevated levels of sialic acid (Sia) in α2,6-linkage (α2,6-Sia) that...

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Detalles Bibliográficos
Autores principales: Byrd-Leotis, Lauren, Jia, Nan, Matsumoto, Yasuyuki, Lu, Dongli, Kawaoka, Yoshihiro, Steinhauer, David A., Cummings, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325728/
https://www.ncbi.nlm.nih.gov/pubmed/35882911
http://dx.doi.org/10.1038/s41598-022-16605-5