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Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold
This paper comprehensively evaluated the static mechanical compressive properties, permeability, and cell adhesion effect on the inner wall of the Primitive triply periodic minimal surface Ti6Al4V bionic scaffolds with different axial diameter ratios through numerical simulation and experiments. The...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325729/ https://www.ncbi.nlm.nih.gov/pubmed/35882907 http://dx.doi.org/10.1038/s41598-022-17066-6 |
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author | Qin, Yaru Wang, Qihui Shi, Chenglong Liu, Bing Ma, Shuqing Zhang, Miao |
author_facet | Qin, Yaru Wang, Qihui Shi, Chenglong Liu, Bing Ma, Shuqing Zhang, Miao |
author_sort | Qin, Yaru |
collection | PubMed |
description | This paper comprehensively evaluated the static mechanical compressive properties, permeability, and cell adhesion effect on the inner wall of the Primitive triply periodic minimal surface Ti6Al4V bionic scaffolds with different axial diameter ratios through numerical simulation and experiments. The results show that when the axial diameter ratio is 1:2, the elastic modulus of the scaffold is about 1.25 and the yield strength is about 1.36. The scaffold's longitudinal and transverse mechanical properties align with human bone tissue. Its permeability is also better than that of circular pores. The scaffold with an axial diameter ratio of 1:3 has the best permeability, ranging from 1.28e−8 to 1.60e−8 m(2), which is more conducive to the adsorption of cells on the inner wall of the scaffold. These results show that the scaffold structure with an axial diameter ratio of not 1:1 has more advantages than the ordinary uniform scaffold structure with an axial diameter ratio of 1:1. This is of great significance to the optimal design of scaffold. |
format | Online Article Text |
id | pubmed-9325729 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-93257292022-07-28 Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold Qin, Yaru Wang, Qihui Shi, Chenglong Liu, Bing Ma, Shuqing Zhang, Miao Sci Rep Article This paper comprehensively evaluated the static mechanical compressive properties, permeability, and cell adhesion effect on the inner wall of the Primitive triply periodic minimal surface Ti6Al4V bionic scaffolds with different axial diameter ratios through numerical simulation and experiments. The results show that when the axial diameter ratio is 1:2, the elastic modulus of the scaffold is about 1.25 and the yield strength is about 1.36. The scaffold's longitudinal and transverse mechanical properties align with human bone tissue. Its permeability is also better than that of circular pores. The scaffold with an axial diameter ratio of 1:3 has the best permeability, ranging from 1.28e−8 to 1.60e−8 m(2), which is more conducive to the adsorption of cells on the inner wall of the scaffold. These results show that the scaffold structure with an axial diameter ratio of not 1:1 has more advantages than the ordinary uniform scaffold structure with an axial diameter ratio of 1:1. This is of great significance to the optimal design of scaffold. Nature Publishing Group UK 2022-07-26 /pmc/articles/PMC9325729/ /pubmed/35882907 http://dx.doi.org/10.1038/s41598-022-17066-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Qin, Yaru Wang, Qihui Shi, Chenglong Liu, Bing Ma, Shuqing Zhang, Miao Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold |
title | Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold |
title_full | Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold |
title_fullStr | Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold |
title_full_unstemmed | Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold |
title_short | Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold |
title_sort | structural design and performance study of primitive triply periodic minimal surfaces ti6al4v biomimetic scaffold |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325729/ https://www.ncbi.nlm.nih.gov/pubmed/35882907 http://dx.doi.org/10.1038/s41598-022-17066-6 |
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