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Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold

This paper comprehensively evaluated the static mechanical compressive properties, permeability, and cell adhesion effect on the inner wall of the Primitive triply periodic minimal surface Ti6Al4V bionic scaffolds with different axial diameter ratios through numerical simulation and experiments. The...

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Autores principales: Qin, Yaru, Wang, Qihui, Shi, Chenglong, Liu, Bing, Ma, Shuqing, Zhang, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325729/
https://www.ncbi.nlm.nih.gov/pubmed/35882907
http://dx.doi.org/10.1038/s41598-022-17066-6
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author Qin, Yaru
Wang, Qihui
Shi, Chenglong
Liu, Bing
Ma, Shuqing
Zhang, Miao
author_facet Qin, Yaru
Wang, Qihui
Shi, Chenglong
Liu, Bing
Ma, Shuqing
Zhang, Miao
author_sort Qin, Yaru
collection PubMed
description This paper comprehensively evaluated the static mechanical compressive properties, permeability, and cell adhesion effect on the inner wall of the Primitive triply periodic minimal surface Ti6Al4V bionic scaffolds with different axial diameter ratios through numerical simulation and experiments. The results show that when the axial diameter ratio is 1:2, the elastic modulus of the scaffold is about 1.25 and the yield strength is about 1.36. The scaffold's longitudinal and transverse mechanical properties align with human bone tissue. Its permeability is also better than that of circular pores. The scaffold with an axial diameter ratio of 1:3 has the best permeability, ranging from 1.28e−8 to 1.60e−8 m(2), which is more conducive to the adsorption of cells on the inner wall of the scaffold. These results show that the scaffold structure with an axial diameter ratio of not 1:1 has more advantages than the ordinary uniform scaffold structure with an axial diameter ratio of 1:1. This is of great significance to the optimal design of scaffold.
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spelling pubmed-93257292022-07-28 Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold Qin, Yaru Wang, Qihui Shi, Chenglong Liu, Bing Ma, Shuqing Zhang, Miao Sci Rep Article This paper comprehensively evaluated the static mechanical compressive properties, permeability, and cell adhesion effect on the inner wall of the Primitive triply periodic minimal surface Ti6Al4V bionic scaffolds with different axial diameter ratios through numerical simulation and experiments. The results show that when the axial diameter ratio is 1:2, the elastic modulus of the scaffold is about 1.25 and the yield strength is about 1.36. The scaffold's longitudinal and transverse mechanical properties align with human bone tissue. Its permeability is also better than that of circular pores. The scaffold with an axial diameter ratio of 1:3 has the best permeability, ranging from 1.28e−8 to 1.60e−8 m(2), which is more conducive to the adsorption of cells on the inner wall of the scaffold. These results show that the scaffold structure with an axial diameter ratio of not 1:1 has more advantages than the ordinary uniform scaffold structure with an axial diameter ratio of 1:1. This is of great significance to the optimal design of scaffold. Nature Publishing Group UK 2022-07-26 /pmc/articles/PMC9325729/ /pubmed/35882907 http://dx.doi.org/10.1038/s41598-022-17066-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Qin, Yaru
Wang, Qihui
Shi, Chenglong
Liu, Bing
Ma, Shuqing
Zhang, Miao
Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold
title Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold
title_full Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold
title_fullStr Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold
title_full_unstemmed Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold
title_short Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold
title_sort structural design and performance study of primitive triply periodic minimal surfaces ti6al4v biomimetic scaffold
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325729/
https://www.ncbi.nlm.nih.gov/pubmed/35882907
http://dx.doi.org/10.1038/s41598-022-17066-6
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