Elucidating the Role of Cerebellar Synaptic Dysfunction in C9orf72-ALS/FTD — a Systematic Review and Meta-Analysis

A hexanucleotide repeat expansion in the C9orf72 gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) with synaptic dysfunction identified as an early pathological hallmark. Although TDP-43 pathology and overt neurodegeneration are largely ab...

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Detalles Bibliográficos
Autores principales: Kaliszewska, Aleksandra, Allison, Joseph, Col, Tarik-Tarkan, Shaw, Christopher, Arias, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325807/
https://www.ncbi.nlm.nih.gov/pubmed/34491551
http://dx.doi.org/10.1007/s12311-021-01320-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325807/
https://www.ncbi.nlm.nih.gov/pubmed/34491551
http://dx.doi.org/10.1007/s12311-021-01320-0

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