Spectroscopic imaging of D-2-hydroxyglutarate and other metabolites in pre-surgical patients with IDH-mutant lower-grade gliomas

PURPOSE: Prognostically favorable IDH-mutant gliomas are known to produce oncometabolite D-2-hydroxyglutarate (2HG). In this study, we investigated metabolite-based features of patients with grade 2 and 3 glioma using 2HG-specific in vivo MR spectroscopy, to determine their relationship with image-g...

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Detalles Bibliográficos
Autores principales: Autry, Adam W., Lafontaine, Marisa, Jalbert, Llewellyn, Phillips, Elizabeth, Phillips, Joanna J., Villanueva-Meyer, Javier, Berger, Mitchel S., Chang, Susan M., Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325821/
https://www.ncbi.nlm.nih.gov/pubmed/35672531
http://dx.doi.org/10.1007/s11060-022-04042-3

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