Neoadjuvant Chemoradiotherapy and Surgery for Esophageal Squamous Cell Carcinoma Versus Definitive Chemoradiotherapy With Salvage Surgery as Needed: The Study Protocol for the Randomized Controlled NEEDS Trial

BACKGROUND: The globally dominant treatment with curative intent for locally advanced esophageal squamous cell carcinoma (ESCC) is neoadjuvant chemoradiotherapy (nCRT) with subsequent esophagectomy. This multimodal treatment leads to around 60% overall 5-year survival, yet with impaired post-surgica...

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Detalles Bibliográficos
Autores principales: Nilsson, Magnus, Olafsdottir, Halla, Alexandersson von Döbeln, Gabriella, Villegas, Fernanda, Gagliardi, Giovanna, Hellström, Mats, Wang, Qiao-Li, Johansson, Hemming, Gebski, Val, Hedberg, Jakob, Klevebro, Fredrik, Markar, Sheraz, Smyth, Elizabeth, Lagergren, Pernilla, Al-Haidari, Ghazwan, Rekstad, Lars Cato, Aahlin, Eirik Kjus, Wallner, Bengt, Edholm, David, Johansson, Jan, Szabo, Eva, Reynolds, John V., Pramesh, CS, Mummudi, Naveen, Joshi, Amit, Ferri, Lorenzo, Wong, Rebecca KS, O’Callaghan, Chris, Lukovic, Jelena, Chan, Kelvin KW, Leong, Trevor, Barbour, Andrew, Smithers, Mark, Li, Yin, Kang, Xiaozheng, Kong, Feng-Ming, Chao, Yin-Kai, Crosby, Tom, Bruns, Christiane, van Laarhoven, Hanneke, van Berge Henegouwen, Mark, van Hillegersberg, Richard, Rosati, Riccardo, Piessen, Guillaume, de Manzoni, Giovanni, Lordick, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326032/
https://www.ncbi.nlm.nih.gov/pubmed/35912196
http://dx.doi.org/10.3389/fonc.2022.917961

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