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Investigating the Role of the NLRP3 Inflammasome Pathway in Acute Intestinal Inflammation: Use of THP-1 Knockout Cell Lines in an Advanced Triple Culture Model

The NLRP3 inflammasome plays an important role in intestinal homeostasis as well as inflammation. However, in vivo studies investigating the role of the NLRP3 inflammasome in inflammatory bowel disease (IBD) report contrasting results, leaving it unclear if the NLRP3 inflammasome augments or attenua...

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Detalles Bibliográficos
Autores principales:	Busch, Mathias, Ramachandran, Haribaskar, Wahle, Tina, Rossi, Andrea, Schins, Roel P. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326178/ https://www.ncbi.nlm.nih.gov/pubmed/35911682 http://dx.doi.org/10.3389/fimmu.2022.898039

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