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Effect of platelet-rich fibrin on extraction socket healing in diabetic patients – A split-mouth crossover study: A prospective clinical trial
AIMS: The aim of this study is to evaluate the effectiveness of platelet-rich fibrin (PRF) in postextraction socket healing in diabetic patients. SUBJECTS AND METHODS: The investigators implemented a randomized, split-mouth study in 100 Type 2 diabetic patients undergoing dental extraction of two or...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326197/ https://www.ncbi.nlm.nih.gov/pubmed/35911800 http://dx.doi.org/10.4103/njms.njms_422_21 |
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author | Asoka, Sangamitra Panneerselvam, Elavenil Pandya, Avadh Rahulbhai Raja, V. B. Krishnakumar Ravi, Poornima |
author_facet | Asoka, Sangamitra Panneerselvam, Elavenil Pandya, Avadh Rahulbhai Raja, V. B. Krishnakumar Ravi, Poornima |
author_sort | Asoka, Sangamitra |
collection | PubMed |
description | AIMS: The aim of this study is to evaluate the effectiveness of platelet-rich fibrin (PRF) in postextraction socket healing in diabetic patients. SUBJECTS AND METHODS: The investigators implemented a randomized, split-mouth study in 100 Type 2 diabetic patients undergoing dental extraction of two or more teeth. Following extraction, the experimental socket was packed with PRF and sutured, while the control socket was sutured without packing. The primary outcome measures were soft-tissue healing (assessed by color, bleeding on palpation, granulation tissue, and incidence of suppuration and dry socket), hard-tissue healing (measured by visual interpretation, area of bone coverage, and grayscale analysis), and visual pain scores. STATISTICAL ANALYSIS: Statistical analysis was done using the independent and paired t-tests, analysis of variance, and Chi-square test RESULTS: Both soft-tissue healing and hard-tissue healing were significantly better in the experimental socket as compared to the control socket. Pain levels, as measured by the visual analog score, were similar in both the extraction sockets. CONCLUSIONS: The use of PRF has beneficial effects in extraction socket healing in diabetic patients. |
format | Online Article Text |
id | pubmed-9326197 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-93261972022-07-28 Effect of platelet-rich fibrin on extraction socket healing in diabetic patients – A split-mouth crossover study: A prospective clinical trial Asoka, Sangamitra Panneerselvam, Elavenil Pandya, Avadh Rahulbhai Raja, V. B. Krishnakumar Ravi, Poornima Natl J Maxillofac Surg Original Article AIMS: The aim of this study is to evaluate the effectiveness of platelet-rich fibrin (PRF) in postextraction socket healing in diabetic patients. SUBJECTS AND METHODS: The investigators implemented a randomized, split-mouth study in 100 Type 2 diabetic patients undergoing dental extraction of two or more teeth. Following extraction, the experimental socket was packed with PRF and sutured, while the control socket was sutured without packing. The primary outcome measures were soft-tissue healing (assessed by color, bleeding on palpation, granulation tissue, and incidence of suppuration and dry socket), hard-tissue healing (measured by visual interpretation, area of bone coverage, and grayscale analysis), and visual pain scores. STATISTICAL ANALYSIS: Statistical analysis was done using the independent and paired t-tests, analysis of variance, and Chi-square test RESULTS: Both soft-tissue healing and hard-tissue healing were significantly better in the experimental socket as compared to the control socket. Pain levels, as measured by the visual analog score, were similar in both the extraction sockets. CONCLUSIONS: The use of PRF has beneficial effects in extraction socket healing in diabetic patients. Medknow Publications & Media Pvt Ltd 2022 2022-04-20 /pmc/articles/PMC9326197/ /pubmed/35911800 http://dx.doi.org/10.4103/njms.njms_422_21 Text en Copyright: © 2022 National Journal of Maxillofacial Surgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Asoka, Sangamitra Panneerselvam, Elavenil Pandya, Avadh Rahulbhai Raja, V. B. Krishnakumar Ravi, Poornima Effect of platelet-rich fibrin on extraction socket healing in diabetic patients – A split-mouth crossover study: A prospective clinical trial |
title | Effect of platelet-rich fibrin on extraction socket healing in diabetic patients – A split-mouth crossover study: A prospective clinical trial |
title_full | Effect of platelet-rich fibrin on extraction socket healing in diabetic patients – A split-mouth crossover study: A prospective clinical trial |
title_fullStr | Effect of platelet-rich fibrin on extraction socket healing in diabetic patients – A split-mouth crossover study: A prospective clinical trial |
title_full_unstemmed | Effect of platelet-rich fibrin on extraction socket healing in diabetic patients – A split-mouth crossover study: A prospective clinical trial |
title_short | Effect of platelet-rich fibrin on extraction socket healing in diabetic patients – A split-mouth crossover study: A prospective clinical trial |
title_sort | effect of platelet-rich fibrin on extraction socket healing in diabetic patients – a split-mouth crossover study: a prospective clinical trial |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326197/ https://www.ncbi.nlm.nih.gov/pubmed/35911800 http://dx.doi.org/10.4103/njms.njms_422_21 |
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