Cargando…

Genetic Diagnostic Yield and Novel Causal Genes of Congenital Heart Disease

Congenital heart disease (CHD) is the most common congenital malformation in fetuses and neonates, which also represents a leading cause of mortality. Although significant progress has been made by emerging advanced technologies in genetic etiology diagnosis, the causative genetic mechanisms behind...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Meihua, Wang, Xinrui, Liu, Hongjie, Peng, Xiaoyan, Yang, You, Yu, Haifei, Xu, Liangpu, Li, Jia, Cao, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326225/ https://www.ncbi.nlm.nih.gov/pubmed/35910219 http://dx.doi.org/10.3389/fgene.2022.941364

Ejemplares similares

Does modeling causal relationships improve the accuracy of predicting lactation milk yields?
por: Wu, Xiao-Lin, et al.
Publicado: (2023)

Causal Inference of Genetic Variants and Genes in Amyotrophic Lateral Sclerosis
por: Pan, Siyu, et al.
Publicado: (2022)

Classifying and Evaluating Fetuses With Ventriculomegaly in Genetic Etiologic Studies
por: Cai, Meiying, et al.
Publicado: (2021)

Genetic diagnostic yields of 354 Chinese ASD children with rare mutations by a pipeline of genomic tests
por: Zhang, Yue, et al.
Publicado: (2023)

Editorial: Crop Yield and Quality Response to the Interaction Between Environment and Genetic Factors
por: Hua, Shuijin, et al.
Publicado: (2022)

Identification of transcription factors MYC and C/EBPβ mediated regulatory networks in heart failure based on gene expression omnibus datasets
por: Wang, Haiwei, et al.
Publicado: (2020)

Exploring the RNA Gap for Improving Diagnostic Yield in Primary Immunodeficiencies
por: Lye, Jed J., et al.
Publicado: (2019)

Bioinformatics searching of diagnostic markers and immune infiltration in polycystic ovary syndrome
por: Yao, Xinrui, et al.
Publicado: (2022)

The genetics of folate metabolism and maternal risk of birth of a child with Down syndrome and associated congenital heart defects
por: Coppedè, Fabio
Publicado: (2015)

Exome sequencing improves genetic diagnosis of congenital orofacial clefts
por: Yan, Shujuan, et al.
Publicado: (2023)

Causal Effects of Genetically Predicted Cystatin C on Osteoporosis: A Two-Sample Mendelian Randomization Study
por: Yuan, Jiaqin, et al.
Publicado: (2022)

Diagnostic Yields of Trio-WES Accompanied by CNVseq for Rare Neurodevelopmental Disorders
por: Gao, Chao, et al.
Publicado: (2019)

Sleep and Late-Onset Alzheimer’s Disease: Shared Genetic Risk Factors, Drug Targets, Molecular Mechanisms, and Causal Effects
por: Chen, Dongze, et al.
Publicado: (2022)

Regular Exercise, Subjective Wellbeing, and Internalizing Problems in Adolescence: Causality or Genetic Pleiotropy?
por: Bartels, Meike, et al.
Publicado: (2012)

cDNA sequencing increases the molecular diagnostic yield in Chediak-Higashi syndrome
por: Kuptanon, Chulaluk, et al.
Publicado: (2023)

Diagnosis, Phenotype, and Molecular Genetics of Congenital Analbuminemia
por: Minchiotti, Lorenzo, et al.
Publicado: (2019)

Determining Genetic Causal Variants Through Multivariate Regression Using Mixture Model Penalty
por: Sundar, V. S., et al.
Publicado: (2018)

Congenital coenzyme Q5-linked pathology: causal genetic association, core phenotype, and molecular mechanism
por: Dawidziuk, Mateusz, et al.
Publicado: (2023)

Exploring the Effect of the Gut Microbiome on the Risk of Age-Related Macular Degeneration From the Perspective of Causality
por: Liu, Kangcheng, et al.
Publicado: (2023)

Diagnostic Yield of Next-Generation Sequencing in Patients With Chronic Kidney Disease of Unknown Etiology
por: de Haan, Amber, et al.
Publicado: (2019)

Cytokinins: A Genetic Target for Increasing Yield Potential in the CRISPR Era
por: Mandal, Sayanti, et al.
Publicado: (2022)

Study of genetic variability, heritability, and genetic advance for yield-related traits in tomato (Solanum lycopersicon MILL.)
por: Rasheed, Adnan, et al.
Publicado: (2023)

An Integrated System Biology Approach Yields Drug Repositioning Candidates for the Treatment of Heart Failure
por: Yang, Guodong, et al.
Publicado: (2019)

Genetic evaluation of patients with congenital heart disease
por: Geddes, Gabrielle C., et al.
Publicado: (2018)

Population Genetic Analysis of Modern and Ancient DNA Variations Yields New Insights Into the Formation, Genetic Structure, and Phylogenetic Relationship of Northern Han Chinese
por: Chen, Pengyu, et al.
Publicado: (2019)

Evaluation of Diagnostic Yield in Fetal Whole-Exome Sequencing: A Report on 45 Consecutive Families
por: Greenbaum, Lior, et al.
Publicado: (2019)

Causal Association Between Heart Failure and Alzheimer’s Disease: A Two-Sample Bidirectional Mendelian Randomization Study
por: Duan, Chenglin, et al.
Publicado: (2022)

BDNF Contributes to the Genetic Variance of Milk Fat Yield in German Holstein Cattle
por: Zielke, Lea G., et al.
Publicado: (2011)

Genetic Analysis of Persistency for Milk Fat Yield in Iranian Buffaloes (Bubalus bubalis)
por: Nazari, Mohammad Ali, et al.
Publicado: (2021)

A Computational Model to Predict the Causal miRNAs for Diseases
por: Gao, Yuanxu, et al.
Publicado: (2019)

Causal Inference for Genetic Obesity, Cardiometabolic Profile and COVID-19 Susceptibility: A Mendelian Randomization Study
por: Aung, Nay, et al.
Publicado: (2020)

Impact of the Order of Legendre Polynomials in Random Regression Model on Genetic Evaluation for Milk Yield in Dairy Cattle Population
por: Li, Jianbin, et al.
Publicado: (2020)

Non-Causal Effects of Asthma on COVID-19 Susceptibility and Severity
por: Qiu, Li-Juan, et al.
Publicado: (2022)

Fetal Congenital Heart Disease Caused by Compound Heterozygous Mutations in the DNAH9 Gene: A Case Report
por: Zhang, Tao, et al.
Publicado: (2022)

The Genetic Causes of Nonsyndromic Congenital Retinal Detachment: A Genetic and Phenotypic Study of Pakistani Families
por: Keser, Vafa, et al.
Publicado: (2017)

Using Genetic Variants to Evaluate the Causal Effect of Plasma Phospholipid Fatty Acids on Breast Cancer and Prostate Cancer: A Mendelian Randomization Study
por: Yang, Ze, et al.
Publicado: (2021)

Assessing Causality in Associations of Serum Calcium and Magnesium Levels With Heart Failure: A Two-Sample Mendelian Randomization Study
por: Helte, Emilie, et al.
Publicado: (2019)

Estimating the frequency of causal genetic variants in foetuses with congenital heart defects: a Chinese cohort study
por: Lu, Fengying, et al.
Publicado: (2022)

Maternal LINE-1 DNA Methylation and Congenital Heart Defects in Down Syndrome
por: Babić Božović, Ivana, et al.
Publicado: (2019)

Accurate determination of causalities in gene regulatory networks by dissecting downstream target genes
por: Jia, Zhigang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cguk1bc7gugbudajuqp62juc69