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Preclinical Evaluation of Fingolimod in Rodent Models of Stroke With Age or Atherosclerosis as Comorbidities

Preclinical data indicate that fingolimod improves outcome post-ischaemia. This study used a rigorous study design in normal male C57BL/6JOlaHsd mice and in mice with common stroke comorbidities to further evaluate the translational potential of fingolimod. Stroke was induced via middle cerebral art...

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Detalles Bibliográficos
Autores principales:	Diaz Diaz, Andrea C., Malone, Kyle, Shearer, Jennifer A., Moore, Anne C., Waeber, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326401/ https://www.ncbi.nlm.nih.gov/pubmed/35910379 http://dx.doi.org/10.3389/fphar.2022.920449

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