Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis

OBJECTIVE: This meta-analysis aims to evaluate the effect of the emerging nutritional ingredient β-hydroxy-β-methylbutyrate (HMB) on the muscle strength of elderly people. METHODS: Computer systems-based search and sorting of relevant documents published before December 2020 in the China Journal Ful...

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Detalles Bibliográficos
Autores principales: Lin, Ziru, Zhao, Anqi, He, Jiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326439/
https://www.ncbi.nlm.nih.gov/pubmed/35911112
http://dx.doi.org/10.3389/fnut.2022.914866
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author Lin, Ziru
Zhao, Anqi
He, Jiguo
author_facet Lin, Ziru
Zhao, Anqi
He, Jiguo
author_sort Lin, Ziru
collection PubMed
description OBJECTIVE: This meta-analysis aims to evaluate the effect of the emerging nutritional ingredient β-hydroxy-β-methylbutyrate (HMB) on the muscle strength of elderly people. METHODS: Computer systems-based search and sorting of relevant documents published before December 2020 in the China Journal Full-text Database (CNKI), Wan Fang Database (Wan Fang), VIP Chinese Science and Technology Journal Database (VIP), PubMed, Web of Science, and EMbase Database was done. Two researchers independently screened the literature based on the inclusion and exclusion criteria and performed data extraction and quality evaluation. Rev Man 5.X software was used for systematic review and meta-analysis. RESULTS: A total of 9 randomized controlled trials (RCT) studies were included in the study, which comprised 896 subjects. The overall impact on muscle strength-related indicators (SMD = 0.41; 95% CI: 0.28, 0.54); p < 0.00001) was statistically significant. Conclusion: Supplementation of HMB and preparations containing HMB ingredients aid in increasing muscle strength in the elderly population.
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spelling pubmed-93264392022-07-28 Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis Lin, Ziru Zhao, Anqi He, Jiguo Front Nutr Nutrition OBJECTIVE: This meta-analysis aims to evaluate the effect of the emerging nutritional ingredient β-hydroxy-β-methylbutyrate (HMB) on the muscle strength of elderly people. METHODS: Computer systems-based search and sorting of relevant documents published before December 2020 in the China Journal Full-text Database (CNKI), Wan Fang Database (Wan Fang), VIP Chinese Science and Technology Journal Database (VIP), PubMed, Web of Science, and EMbase Database was done. Two researchers independently screened the literature based on the inclusion and exclusion criteria and performed data extraction and quality evaluation. Rev Man 5.X software was used for systematic review and meta-analysis. RESULTS: A total of 9 randomized controlled trials (RCT) studies were included in the study, which comprised 896 subjects. The overall impact on muscle strength-related indicators (SMD = 0.41; 95% CI: 0.28, 0.54); p < 0.00001) was statistically significant. Conclusion: Supplementation of HMB and preparations containing HMB ingredients aid in increasing muscle strength in the elderly population. Frontiers Media S.A. 2022-07-13 /pmc/articles/PMC9326439/ /pubmed/35911112 http://dx.doi.org/10.3389/fnut.2022.914866 Text en Copyright © 2022 Lin, Zhao and He. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Lin, Ziru
Zhao, Anqi
He, Jiguo
Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis
title Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis
title_full Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis
title_fullStr Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis
title_full_unstemmed Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis
title_short Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis
title_sort effect of β-hydroxy-β-methylbutyrate (hmb) on the muscle strength in the elderly population: a meta-analysis
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326439/
https://www.ncbi.nlm.nih.gov/pubmed/35911112
http://dx.doi.org/10.3389/fnut.2022.914866
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AT hejiguo effectofbhydroxybmethylbutyratehmbonthemusclestrengthintheelderlypopulationametaanalysis

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