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The Therapeutic Potential of Targeting NIK in B Cell Malignancies
NF-κB-inducing kinase (NIK) is a key player in non-canonical NF-κB signaling, involved in several fundamental cellular processes, and is crucial for B cell function and development. In response to certain signals and ligands, such as CD40, BAFF and lymphotoxin-β activation, NIK protein stabilization...
Autores principales: | Haselager, Marco V., Eldering, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326486/ https://www.ncbi.nlm.nih.gov/pubmed/35911754 http://dx.doi.org/10.3389/fimmu.2022.930986 |
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